Evidence map›Paper›PMID 31283528›Full record

ReviewExercise and sport sciences reviews2019

Training-Induced Neural Plasticity and Strength Are Amplified After Stroke.

Yao Sun, E Paul Zehr

Registry-linked trialAbstract readReview
In one paragraph

Review in Exercise and sport sciences reviews, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06817512 (Health Effects of Vitamin K2 Supplementation on Skeletal Muscle and Neurological Function After Ischemic Stroke), which is not on this map. Cited by 27 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06817512 naactive not recruitingnot on this mapstarted 2025, after this paper: background citation

Health Effects of Vitamin K2 Supplementation on Skeletal Muscle and Neurological Function After Ischemic Stroke

TypeinterventionalSponsorHarbin Medical UniversityRan2025 to 2028Enrolled190ConditionsIschemic StrokeArmsVitamin K2, Placebo
3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
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  15. Sarcopenia and nervous system disorders.Journal of neurology · 2022
    Review
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  20. Users' experience of community-based power assisted exercise: a transition from NHS to third sector services.International journal of qualitative studies on health and well-being · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Yao SunRehabilitation Neuroscience Laboratory, University of Victoria, Victoria, BC.
E Paul ZehrRehabilitation Neuroscience Laboratory, University of Victoria, Victoria, BC.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Following stroke, sensorimotor brain networks and descending regulation are compromised but spinal interlimb neural connections remain morphologically intact. After cross-education strength and locomotion training, amplified neural plasticity and functional responses are observed in chronic stroke compared with neurologically intact participants. We hypothesize that poststroke neuroplasticity is amplified because of the involvement of interlimb neural connections that persist from our quadrupedal ancestry.

Indexed as

Neuronal PlasticityStroke RehabilitationArmExercise TherapyHumansLegMuscle StrengthNerve NetNeural PathwaysPhysical Conditioning, HumanStroke

Identifiers

PMID31283528
PMCPMC6887626

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.