Evidence map›Paper›PMID 31283406›Full record

ArticleJournal of clinical oncology : official journal of the American Society of Clinical Oncology2019

Patient-Perceived Lack of Choice in Receipt of Radioactive Iodine for Treatment of Differentiated Thyroid Cancer.

Lauren P Wallner, David Reyes-Gastelum, Ann S Hamilton, Kevin C Ward, Sarah T Hawley, Megan R Haymart

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06980103 (Use of a Decision Aid to Resolve Uncertainty About Radioactive Iodine Treatment in Patients With Intermediate Risk Thyroid Cancer), which is not on this map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
4.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06980103 narecruitingnot on this mapstarted 2025, after this paper: background citation

Use of a Decision Aid to Resolve Uncertainty About Radioactive Iodine Treatment in Patients With Intermediate Risk Thyroid Cancer: The Radiance Trial

TypeinterventionalSponsorGeorgetown UniversityRan2025 to 2029Enrolled408ConditionsThyroid CancerArmsDecision Aid, Usual Care
3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.

  1. Guideline
  2. Article
  3. Review
  4. Article
  5. Review
  6. Change in worry over time among Hispanic women with thyroid cancer.Journal of cancer survivorship : research and practice · 2022
    Article
  7. Disparities in Thyroid Care.Endocrinology and metabolism clinics of North America · 2022
    Review
  8. Radioactive iodine therapy: multiple faces of the same polyhedron.Archives of endocrinology and metabolism · 2022
    Review
  9. Article
  10. Article
  11. Thyrotropin Suppression for Papillary Thyroid Cancer: A Physician Survey Study.Thyroid : official journal of the American Thyroid Association · 2021
    Article
  12. Physician management of thyroid cancer patients' worry.Journal of cancer survivorship : research and practice · 2021
    Article
  13. Article
  14. Article
  15. Patient Perspectives on the Extent of Surgery and Radioactive Iodine Treatment for Low-Risk Differentiated Thyroid Cancer.Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists · 2021
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. The Year in Medical Thyroidology Review: Current Challenges and Future Directions.Thyroid : official journal of the American Thyroid Association · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Lauren P Wallner1University of Michigan, Ann Arbor, MI.
David Reyes-Gastelum1University of Michigan, Ann Arbor, MI.
Ann S Hamilton2University of Southern California Keck School of Medicine, Los Angeles, CA.
Kevin C Ward3Emory University, Atlanta, GA.
Sarah T Hawley1University of Michigan, Ann Arbor, MI.
Megan R Haymart1University of Michigan, Ann Arbor, MI.
University of Michigan–Ann Arbor · USEmory University · USUniversity of Southern California · US

Funding

CALIFORNIA COORDINATED CANCER PREVENTION & CONTROL PROGRAMU58DP003862 · DP · CALIFORNIA STATE DEPT OF PUBLIC HEALTH · PI SNIPES, KURT P · 2012 to 2014
$31.5M
GEORGIA COMPREHENSIVE CANCER CONTROL PROGRAMU58DP003875 · DP · GEORGIA DIVISION OF PUBLIC HEALTH · PI O'CONNOR, JEAN CATHERINE · 2012 to 2014
$15.9M
Treatment decision making in low-risk thyroid cancerR01CA201198 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI HAYMART, MEGAN RIST · 2016 to 2019
$2.4M
Patient-centered, team-based continuing care after breast cancer treatmentK07CA201052 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI WALLNER, LAUREN P · 2016 to 2019
$601k
NCCDPHP CDC HHS U58 DP003862NCCDPHP CDC HHS U58 DP003875NCI NIH HHS HHSN261201000035CNCI NIH HHS HHSN261201000035INCI NIH HHS HHSN261201800003CNCI NIH HHS K07 CA201052NCI NIH HHS R01 CA201198
6 · The paper itself

Abstract

purposeFor many patients with differentiated thyroid cancer, use of radioactive iodine (RAI) does not improve survival or reduce recurrence risk. Yet there is wide variation in RAI use, emphasizing the importance of understanding patient perspectives regarding RAI decision making. PATIENTS AND

methodsAll eligible patients diagnosed with thyroid cancer from 2014 to 2015 from the Georgia and Los Angeles SEER registries were surveyed (N = 2,632; response rate, 63%). Patients in whom selective RAI use is recommended were included in this analysis (n = 1,319). Patients were asked whether they felt like they had a choice to receive RAI (yes or no), how strongly their physician recommended RAI (5-point Likert-type scale), whether they received RAI (yes or no), and how satisfied they were with their RAI decision (more [score of 4 or greater]

resultsMore than half of respondents (55.8%) perceived they did not have an RAI choice, and the majority of patients (75.9%) received RAI. The odds of perceiving no RAI choice was greater among those whose physician strongly recommended RAI (adjusted odds ratio [OR], 1.56; 95% CI, 1.13 to 2.17). Patients who perceived they did not have an RAI choice were more likely to receive RAI (adjusted OR, 2.50; 95% CI, 1.64 to 3.82) and report lower decision satisfaction (adjusted OR, 2.31; 95% CI, 1.67 to 3.20).

conclusionMany patients did not feel they had a choice about whether to receive RAI. Patients who perceived they did not have a choice were more likely to receive RAI and report lower decision satisfaction, suggesting a need for more shared decision making to reduce overtreatment.

Indexed as

AdultAgedCell DifferentiationFemaleGeorgiaGuideline AdherenceHumansIodine RadioisotopesLos AngelesMaleMiddle AgedPatient Acceptance of Health CarePatient PreferencePatient SatisfactionRegistriesSEER ProgramIodine Radioisotopes

Identifiers

PMID31283406
PMCPMC6698919
OpenAlexW2961454944

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.