Evidence map›Paper›PMID 31283378›Full record

ReviewAnnual review of cell and developmental biology2019

Shared Transcriptional Control of Innate Lymphoid Cell and Dendritic Cell Development.

Prachi Bagadia, Xiao Huang, Tian-Tian Liu, Kenneth M Murphy

Open access · bronzeAbstract readReview
In one paragraph

Review in Annual review of cell and developmental biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. The evolving biology of cross-presentation.Seminars in immunology · 2023
    Review
  6. Review
  7. Article
  8. Article
  9. Review
  10. Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Prachi BagadiaDepartment of Pathology and Immunology, Washington University School of Medicine, St. Louis, Missouri 63108, USA; email: kmurphy@wustl.edu.
Xiao HuangDepartment of Pathology and Immunology, Washington University School of Medicine, St. Louis, Missouri 63108, USA; email: kmurphy@wustl.edu.
Tian-Tian LiuDepartment of Pathology and Immunology, Washington University School of Medicine, St. Louis, Missouri 63108, USA; email: kmurphy@wustl.edu.
Kenneth M MurphyDepartment of Pathology and Immunology, Washington University School of Medicine, St. Louis, Missouri 63108, USA; email: kmurphy@wustl.edu.
Washington University in St. Louis · USHoward Hughes Medical Institute · US

Funding

Molecular Basis of cDC1 DevelopmentR01AI162643 · NIAID · WASHINGTON UNIVERSITY · PI MURPHY, KENNETH M · 2022 to 2025
$2.8M
Function of Wdfy4 in cross-presentation and immunityR01AI150297 · NIAID · WASHINGTON UNIVERSITY · PI MURPHY, KENNETH M · 2019 to 2023
$2.5M
Understanding the Mechanisms of DC Licensing in CD8 T Cell PrimingR01CA248919 · NCI · WASHINGTON UNIVERSITY · PI MURPHY, KENNETH M · 2021 to 2025
$2.3M
Howard Hughes Medical InstituteNCI NIH HHS R01 CA248919NIAID NIH HHS R01 AI150297NIAID NIH HHS R01 AI162643
6 · The paper itself

Abstract

Innate immunity and adaptive immunity consist of highly specialized immune lineages that depend on transcription factors for both function and development. In this review, we dissect the similarities between two innate lineages, innate lymphoid cells (ILCs) and dendritic cells (DCs), and an adaptive immune lineage, T cells. ILCs, DCs, and T cells make up four functional immune modules and interact in concert to produce a specified immune response. These three immune lineages also share transcriptional networks governing the development of each lineage, and we discuss the similarities between ILCs and DCs in this review.

Indexed as

Adaptive ImmunityGene Regulatory NetworksAnimalsCell DifferentiationCytokinesDendritic CellsGene Expression RegulationHumansImmunity, InnateLymphocytesT-LymphocytesTranscription FactorsCytokinesTranscription Factorsdendritic cellshematopoiesisinnate lymphoid cellsT cellstranscription factors

Identifiers

PMID31283378
PMCPMC6886469
OpenAlexW2961156677

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.