Evidence map›Paper›PMID 31283358›Full record

ReviewAnnual review of genetics2019

Donghoon M Lee, Elizabeth H Chen

Abstract readReview
In one paragraph

Review in Annual review of genetics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Donghoon M LeeDepartment of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA; email: Elizabeth.Chen@UTSouthwestern.edu.
Elizabeth H ChenDepartment of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA; email: Elizabeth.Chen@UTSouthwestern.edu.

Funding

Molecular Mechanisms of Myoblast FusionR01AR053173 · NIAMS · UT SOUTHWESTERN MEDICAL CENTER · PI CHEN, ELIZABETH H · 2006 to 2022
$5.3M
Dissecting the Mechanisms of Cell-Cell Fusion Using A Cell Culture SystemR01GM098816 · NIGMS · UT SOUTHWESTERN MEDICAL CENTER · PI CHEN, ELIZABETH H · 2012 to 2019
$2.9M
Canadian Institute of Health ResearchHoward Hughes Medical InstituteNIAMS NIH HHS R01 AR053173NIGMS NIH HHS R01 GM098816
6 · The paper itself

Abstract

Cell-cell fusion is indispensable for creating life and building syncytial tissues and organs. Ever since the discovery of cell-cell fusion, how cells join together to form zygotes and multinucleated syncytia has remained a fundamental question in cell and developmental biology. In the past two decades,

Indexed as

ActinsActomyosinAnimalsCell Adhesion MoleculesCell FusionDrosophilaDrosophila ProteinsEmbryo, NonmammalianLipid BilayersMusclesMyoblastsPupaActinsActomyosinCell Adhesion MoleculesDrosophila ProteinsLipid Bilayersactin-propelled membrane protrusionsasymmetric fusogenic synapsecell–cell fusionDrosophila geneticsmechanical tensionmechanosensory responsemyoblast fusion

Identifiers

PMID31283358
PMCPMC7448821

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.