Evidence map›Paper›PMID 31282228›Full record

ArticleJournal of enzyme inhibition and medicinal chemistry2019

Seeking new approach for therapeutic treatment of cholera disease via inhibition of bacterial carbonic anhydrases: experimental and theoretical studies for sixteen benzenesulfonamide derivatives.

Rosaria Gitto, Laura De Luca, Francesca Mancuso, Sonia Del Prete, Daniela Vullo, Claudiu T Supuran, Clemente Capasso

Open access · goldAbstract read
In one paragraph

Article in Journal of enzyme inhibition and medicinal chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Activation of the β-carbonic anhydrase from the protozoan pathogenJournal of enzyme inhibition and medicinal chemistry · 2021
    Article
  3. Anion inhibition studies of the α-carbonic anhydrases fromJournal of enzyme inhibition and medicinal chemistry · 2021
    Article
  4. An anion and small molecule inhibition study of the β-carbonic anhydrase fromJournal of enzyme inhibition and medicinal chemistry · 2021
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Rosaria Gittoa Department of Chemical, Biological, Pharmaceutical and Environmental Sciences (CHIBIOFARAM) , University of Messina , Messina , Italy.ORCID http://orcid.org/0000-0003-0002-2253
Laura De Lucaa Department of Chemical, Biological, Pharmaceutical and Environmental Sciences (CHIBIOFARAM) , University of Messina , Messina , Italy.
Francesca Mancusoa Department of Chemical, Biological, Pharmaceutical and Environmental Sciences (CHIBIOFARAM) , University of Messina , Messina , Italy.
Sonia Del Preteb Department of Biology , Agriculture and Food Sciences, Institute of Biosciences and Bioresources- CNR , Napoli , Italy.
Daniela Vulloc NUROFARBA Department , University of Florence , Sesto Fiorentino , Italy.
Claudiu T Supuranc NUROFARBA Department , University of Florence , Sesto Fiorentino , Italy.ORCID http://orcid.org/0000-0003-4262-0323
Clemente Capassob Department of Biology , Agriculture and Food Sciences, Institute of Biosciences and Bioresources- CNR , Napoli , Italy.ORCID http://orcid.org/0000-0003-3314-2411
University of Messina · ITInstitute of Biosciences and Bioresources · ITUniversity of Florence · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A series of sixteen benzenesulfonamide derivatives has been synthesised and tested as inhibitors of

Indexed as

BenzenesulfonamidesCarbonic Anhydrase InhibitorsCholeraHumansHydrophobic and Hydrophilic InteractionsIsoenzymesMolecular Docking SimulationStructure-Activity RelationshipSulfonamidesVibrio choleraeBenzenesulfonamidesCarbonic Anhydrase InhibitorsIsoenzymesSulfonamidesbenzenesulfonamidesCarbonic anhydrase inhibitors (CAIs)molecular docking

Identifiers

PMID31282228
PMCPMC6691843
OpenAlexW2957946745

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.