Evidence map›Paper›PMID 31281938›Full record

Trial reportIndian journal of pediatrics2019

Effects of Exercise Intervention Program on Bone Mineral Accretion in Children and Adolescents with Cystic Fibrosis: A Randomized Controlled Trial.

Sumita Gupta, Aparna Mukherjee, Rakesh Lodha, Madhulika Kabra, Kishore K Deepak, Rajesh Khadgawat, Anjana Talwar, Sushil Kumar Kabra

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Indian journal of pediatrics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 3 pooled it
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 3 syntheses or guidelines pooled it, 26 citations in OpenAlex.

  1. The 2025 European Cystic Fibrosis Society position statement on physical activity assessment in cystic fibrosis.European respiratory review : an official journal of the European Respiratory Society · 2025
    Guideline
  2. Physical activity and exercise training in cystic fibrosis.The Cochrane database of systematic reviews · 2022
    Pooled it
  3. Physical exercise training for cystic fibrosis.The Cochrane database of systematic reviews · 2017
    Pooled it
  4. The location of physical activity determines its efficacy on Vitamin D status: Evidence from a meta-analysis.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2026
    Review
  5. Review
  6. Cystic fibrosis-related bone disease: an update on screening, diagnosis, and treatment.Therapeutic advances in endocrinology and metabolism · 2025
    Review
  7. Review
  8. Article
  9. Review
  10. Review
  11. Review
  12. Review
  13. Article
  14. Exercise for Healthy Lungs.Indian journal of pediatrics · 2019
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Sumita GuptaDepartment of Pediatrics, All India Institute of Medical Sciences, New Delhi, 110029, India.
Aparna MukherjeeDepartment of Pediatrics, All India Institute of Medical Sciences, New Delhi, 110029, India.
Rakesh LodhaDepartment of Pediatrics, All India Institute of Medical Sciences, New Delhi, 110029, India.
Madhulika KabraDepartment of Pediatrics, All India Institute of Medical Sciences, New Delhi, 110029, India.
Kishore K DeepakDepartment of Physiology, All India Institute of Medical Sciences, New Delhi, India.
Rajesh KhadgawatDepartment of Endocrinology, All India Institute of Medical Sciences, New Delhi, India.
Anjana TalwarDepartment of Physiology, All India Institute of Medical Sciences, New Delhi, India.
Sushil Kumar KabraDepartment of Pediatrics, All India Institute of Medical Sciences, New Delhi, 110029, India. skkabra@hotmail.com.
All India Institute of Medical Sciences · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate effect of one year exercise intervention program on bone mineral accrual in children and adolescent with cystic fibrosis (CF).

methodsFifty-two CF children (mean age 149.79 mo) were randomized into experimental (15 boys and 10 girls) and control groups (15 boys and 12 girls). Experimental group performed prescribed exercises three times/week, while control group continued with routine physical activities for one year. Following were assessed at baseline and at one year: Bone mineral density (BMD) of whole body and lumbar spine, pulmonary function, exercise capacity, quality of life and habitual activity.

resultsChange in whole body and lumbar spine BMD over 12 mo in experimental group was lower by 0.006 g/cm

conclusionsExercise regime was not associated with significant improvement in BMD of CF patients, but it had a positive impact on both physical and psychological health of these patients.

Indexed as

Bone DensityCalcification, PhysiologicAdolescentChildCystic FibrosisExerciseExercise TherapyFemaleHumansIndiaLumbar VertebraeMaleQuality of LifeSurveys and QuestionnairesVitamin DVitamin DBone mineral densityCystic fibrosisExerciseExercise capacityQuality of lifeVitamin D

Identifiers

PMID31281938
OpenAlexW2953868229

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.