ArticleBioMed research international2019
Low Bioelectrical Impedance Phase Angle Is a Significant Risk Factor for Frailty.
Article in BioMed research international, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05991778 (Bioelectrical Impedance Vector Analysis), which is not on this map. Cited by 40 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Bioelectrical Impedance Vector Analysis (BIVA) in Monitoring Hyperhydration and Polyneuromyopathy in Critically Ill Patients
Who cites it
40 citing papers in PubMed.
- Bioelectrical Impedance in Monitoring Hyperhydration and Muscle Wasting in Critically Ill Corona Virus Disease (COVID-19) Patients: The Feasibility of Predicting Outcome.Physiological research · 2025Trial
- Trial
- Bioelectrical impedance phase angle is associated with physical performance before but not after simulated multi-stressor military operations.Physiological reports · 2023Trial
- Effects of a new respiratory muscle training device in community-dwelling elderly men: an open-label, randomized, non-inferiority trial.BMC geriatrics · 2022Trial
- A Randomized, Controlled Trial Comparing the Impact of a Low-Calorie Ketogenic vs a Standard Low-Calorie Diet on Fat-Free Mass in Patients Receiving an Elipse™ Intragastric Balloon Treatment.Obesity surgery · 2021Trial
- Lower Limb Phase Angle Correlates Most with Locomotive Syndrome and Walking Function in Patients with Lumbar Spinal Stenosis: A Retrospective Study.Spine surgery and related research · 2026Article
- Observational
- Relationship between Early Postoperative Regional Phase Angle and Walking Ability in Older Adult Patients with Hip Fracture.Progress in rehabilitation medicine · 2026Article
- Segmental Bioimpedance Phase Angles for Frailty Detection in Hospitalized Older Adults with Cardiovascular Disease: A Cross-Sectional Observational Study.Healthcare (Basel, Switzerland) · 2025Article
- Usefulness of the Phase Angle in Evaluating Locomotive Syndrome in Cancer Patients.Journal of clinical medicine · 2025Article
- Application of Levi's Muscle Index in frailty assessment: comparison of bioimpedance measures among older adults.Frontiers in medicine · 2025Article
- Phase angle in bioelectrical impedance analysis for assessing congestion in acute heart failure.PloS one · 2025Article
- Tracking the Plasma C-Terminal Agrin Fragment as a Biomarker of Neuromuscular Decline in 18- to 87-Year-Old Men.Molecular diagnosis & therapy · 2024Article
- Association between preoperative phase angle and all-cause mortality after cardiovascular surgery: A retrospective cohort study.Journal of cachexia, sarcopenia and muscle · 2024Article
- To Be Frail or Not to Be Frail: This Is the Question-A Critical Narrative Review of Frailty.Journal of clinical medicine · 2024Review
- Article
- Associations of Lower-Limb Phase Angle with Locomotion and Motor Function in Japanese Community-Dwelling Older Adults.Geriatrics (Basel, Switzerland) · 2023Article
- Body composition phase angle: A potential predictor of vitamin D status in early pregnancy.Food science & nutrition · 2023Article
- Reduced body cell mass and functions in lower extremities are associated with mild cognitive impairment and Alzheimer's dementia.Scientific reports · 2023Article
- Role of phase angle in older adults with focus on the geriatric syndromes sarcopenia and frailty.Reviews in endocrine & metabolic disorders · 2023Review
Corrections and comments
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Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The phase angle, which is measured via bioelectrical impedance analysis (BIA), is a clinically important bioimpedance parameter used for nutritional assessment and evaluating the risk of various diseases, such as locomotive syndrome (LS). It remains unclear if the phase angle is associated with frailty (fragile state of physical and mental health). We therefore examined this association in a large prospective sample. Of 1081 individuals receiving health checkups, 550 (male; 235, female; 365) were enrolled in this study. We applied the Japanese version of the Cardiovascular Health Study criteria to evaluate frailty and administered the 25-Item Geriatric Locomotive Function Scale to diagnose LS. The phase angle was measured via BIA. Multiple logistic regression analysis was used to evaluate the relationship between the phase angle and frailty. For all participants and for each sex, the phase angle was significantly lower among individuals with frailty. After controlling for age, sex, and body mass index, we found that a low phase angle was a significant risk factor of frailty. As a result of multiple regression analysis including other confounding factors, among male participants, a low phase angle was significantly related with both frailty (
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