ArticleFrontiers in cellular and infection microbiology2019
Identification of Salivary Microbiota and Its Association With Host Inflammatory Mediators in Periodontitis.
Article in Frontiers in cellular and infection microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 82 papers, 1 of them a synthesis that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
82 citing papers in PubMed, 1 synthesis or guideline pooled it, 124 citations in OpenAlex.
- Pooled it
- Anti-inflammatory and antimicrobial efficacy of coconut oil for periodontal pathogens: a triple-blind randomized clinical trial.Clinical oral investigations · 2025Trial
- Analgesic Efficacy of Curcuma longa (Curcumin) after Surgical Periodontal Therapy.Oral health & preventive dentistry · 2022Trial
- Functional Foods and Micro- and Nanoplastics: Advances in Precision Nutritional Medicine for Oral-Gut-Brain Axis Health.Antioxidants (Basel, Switzerland) · 2026Review
- [The Role of Salivary Microbiota in Oral and Systemic Disease Development and Diagnosis].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2026Review
- Oral-Rinse-Sourced Microbiota in Oral Health and Diseases in a Representative US Adult Population: Implications for Diagnostics.Journal of clinical periodontology · 2026Article
- From health to periodontitis: dynamic changes in the subgingival microbiome and their association with systemic inflammation levels.Frontiers in cellular and infection microbiology · 2026Article
- Integration of periodontal pathogens and inflammatory mediators in saliva as biomarkers for periodontitis.Frontiers in cellular and infection microbiology · 2026Article
- Characterisation of the gut-lung axis microbiome in clinically stable patients with chronic obstructive pulmonary disease.EBioMedicine · 2026Observational
- The impact of organ transplantation on changes in the oral microbiome, particularly on bacteria causing periodontal inflammation - narrative review.Frontiers in cellular and infection microbiology · 2026Review
- Periodontitis salivary microbiota exacerbates colitis by CXCL3 derived from gut microbiota-induced macrophages.Microbiome · 2025Article
- The Precision Paradigm in Periodontology: A Multilevel Framework for Tailored Diagnosis, Treatment, and Prevention.Journal of personalized medicine · 2025Review
- DnaK of Parvimonas micra extracellular vesicles interacts with the host fibroblasts BAG3-IKK-γ axis to accelerate TNF-α secretion in oral lichen planus.Microbiome · 2025Article
- Salivary Inflammatory Mediator Profiles in Periodontal and Peri-Implant Health and Disease: A Cross-Sectional Study.Clinical implant dentistry and related research · 2025Article
- The oral microbiome in aging: a window into health and longevity.Journal of oral microbiology · 2025Review
- EPheClass: ensemble-based phenotype classifier from 16S rRNA gene sequences.Frontiers in bioinformatics · 2025Article
- Alterations of the salivary microbiome in obstructive sleep apnea and their association with periodontitis.Frontiers in cellular and infection microbiology · 2025Article
- Comprehensive analysis of transcriptome and microbiome in colorectal cancer with synchronous polyp patients.Frontiers in cellular and infection microbiology · 2025Article
- Quantifying periodontitis-associated oral dysbiosis in tongue and saliva microbiomes-An integrated data analysis.Journal of periodontology · 2025Article
- Significance of IL-8 and HMGB1 expression in peripheral blood and gingival sulcus fluid of patients with chronic periodontitis.American journal of translational research · 2025Article
22 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Periodontitis is a microbial-induced chronic inflammatory disease, which may not only result in tooth loss, but can also contribute to the development of various systemic diseases. The transition from healthy to diseased periodontium depends on microbial dysbiosis and impaired host immune response. Although periodontitis is a common disease as well as associated with various systemic inflammatory conditions, the taxonomic profiling of the salivary microbiota in periodontitis and its association with host immune and inflammatory mediators has not been reported. Therefore, the aim of this study was to identify key pathogens and their potential interaction with the host's inflammatory mediators in saliva samples for periodontitis risk assessment. The microbial 16S rRNA gene sequencing and the levels of inflammatory mediators were performed in saliva samples from patients with chronic periodontitis and periodontally healthy control subjects. The salivary microbial community composition differed significantly between patients with chronic periodontitis and healthy controls. Our analyses identified a number of microbes, including bacteria assigned to
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.