ArticleFrontiers in cellular and infection microbiology2019
Eucalyptal D Enhances the Antifungal Effect of Fluconazole on Fluconazole-Resistant
Article in Frontiers in cellular and infection microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 29 citations in OpenAlex.
- Optimization of an antifungal formulation based on eucalyptol, β-pinene, and α-terpinene against Candida albicans and Candida glabrata: A mixture design study.Naunyn-Schmiedeberg's archives of pharmacology · 2026Article
- Exploring the Mechanism of Tannic Acid AgainstPathogens (Basel, Switzerland) · 2026Article
- Celastrol boosts fluconazole efficacy against vaginal candidiasis: in vitro and in vivo evidence.AMB Express · 2025Article
- Is there a difference in the expression levels of genes responsible for fluconazole resistance inCurrent medical mycology · 2025Review
- Plant-Derived Terpenoids: A Plethora of Bioactive Compounds with Several Health Functions and Industrial Applications-A Comprehensive Overview.Molecules (Basel, Switzerland) · 2024Review
- The anti-staphylococcal fusidic acid as an efflux pump inhibitor combined with fluconazole against vaginal candidiasis in mouse model.BMC microbiology · 2024Article
- Synergistic activity of the combination of falcarindiol and itraconazoleFrontiers in cellular and infection microbiology · 2023Article
- Augmenting Azoles with Drug Synergy to Expand the Antifungal Toolbox.Pharmaceuticals (Basel, Switzerland) · 2022Review
- New Peptide Based Fluconazole Conjugates with Expanded Molecular Targets.Pharmaceutics · 2022Article
- Herbal Products and Their Active Constituents Used Alone and in Combination with Antifungal Drugs against Drug-ResistantAntibiotics (Basel, Switzerland) · 2021Review
- Plant-Derived Substances in the Fight Against Infections Caused byInternational journal of molecular sciences · 2020Review
- Synergistic Effects of Efflux Pump Modulators on the Azole Antifungal Susceptibility of Microsporum canis.Mycopathologia · 2020Article
- Synergistic Effect of Berberine Hydrochloride and Fluconazole AgainstFrontiers in microbiology · 2020Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The frequent emergence of azole-resistant strains has increasingly led azoles to fail in treating candidiasis. Combination with other drugs is a good option to effectively reduce or retard its incidence of resistance. Natural products are a promising synergist source to assist azoles in treating resistant candidiasis. Eucalyptal D (ED), a formyl-phloroglucinol meroterpenoid, is one of the natural synergists, which could significantly enhance the anticandidal activity of fluconazole (FLC) in treating FLC resistant
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.