Evidence map›Paper›PMID 31281772›Full record

ArticleQuantitative imaging in medicine and surgery2019

Multi-scale and -contrast sensorless adaptive optics optical coherence tomography.

Myeong Jin Ju, Destiny Hsu, Ji Hoon Kwon, Daniel J Wahl, Stefano Bonora, Yifan Jian, Shuichi Makita, Yoshiaki Yasuno, Marinko V Sarunic

Open access · diamondAbstract read
In one paragraph

Article in Quantitative imaging in medicine and surgery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Quantitative multi-contrastBiomedical optics express · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 5 countries.

Myeong Jin JuDepartment of Engineering Science, Simon Fraser University, Burnaby, Canada.
Destiny HsuDepartment of Engineering Science, Simon Fraser University, Burnaby, Canada.
Ji Hoon KwonDepartment of Engineering Science, Simon Fraser University, Burnaby, Canada.
Daniel J WahlDepartment of Engineering Science, Simon Fraser University, Burnaby, Canada.
Stefano BonoraCNR-Institute for Photonics and Nanotechnology, Padova, Italy.
Yifan JianCasey Eye Institute, Oregon Health & Science University, Portland, Oregon, USA.
Shuichi MakitaComputational Optics Group, University of Tsukuba, Tsukuba, Ibaraki, Japan.
Yoshiaki YasunoComputational Optics Group, University of Tsukuba, Tsukuba, Ibaraki, Japan.
Marinko V SarunicDepartment of Engineering Science, Simon Fraser University, Burnaby, Canada.
Simon Fraser University · CAUniversity of Tsukuba · JPCenter for Biomolecular Nanotechnologies · ITDankook University · KROregon Health & Science University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe roles of the retinal microvasculature and the retinal pigment epithelium (RPE) in maintaining the health and metabolic activity of the retina lend great clinical value to their high-resolution visualization.

methodsBy integrating polarization diversity detection (PDD) into multi-scale and -contrast sensorless adaptive optics optical coherence tomography (MSC-SAO-OCT), we have developed a novel multi-contrast SAO OCT system for imaging pigment in the RPE as well as flow in the retinal capillaries using OCT angiography (OCTA). Aberration correction was performed based on the image quality using transmissive deformable optical elements.

resultsMSC-SAO-OCTA imaging was performed at multiple fields-of-view (FOVs) with adjustable numerical aperture (NA). Retinal flow and RPE structural images for

conclusionsHigh-resolution imaging of retinal vasculature at both large and small FOVs, as well as characterization of RPE topology and deformation, enables more sophisticated and concise investigation of retinal pathologies for

Indexed as

adaptive opticsangiographyophthalmologyOptical coherence tomography (OCT)polarimetric imagingretina

Identifiers

PMID31281772
PMCPMC6571195
OpenAlexW2945053806

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.