Evidence map›Paper›PMID 31281565›Full record

ArticleOxidative medicine and cellular longevity2019

Suppression of Mouse AApoAII Amyloidosis Progression by Daily Supplementation with Oxidative Stress Inhibitors.

Jian Dai, Xin Ding, Hiroki Miyahara, Zhe Xu, Xiaoran Cui, Yuichi Igarashi, Jinko Sawashita, Masayuki Mori, Keiichi Higuchi

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Jian DaiDepartment of Aging Biology, Institute of Pathogenesis and Disease Prevention, Shinshu University Graduate School of Medicine, Matsumoto 390-8621, Japan.ORCID 0000-0001-8097-6756
Xin DingDepartment of Aging Biology, Institute of Pathogenesis and Disease Prevention, Shinshu University Graduate School of Medicine, Matsumoto 390-8621, Japan.ORCID 0000-0003-0571-315X
Hiroki MiyaharaDepartment of Aging Biology, Institute of Pathogenesis and Disease Prevention, Shinshu University Graduate School of Medicine, Matsumoto 390-8621, Japan.ORCID 0000-0003-0548-9944
Zhe XuDepartment of Aging Biology, Institute of Pathogenesis and Disease Prevention, Shinshu University Graduate School of Medicine, Matsumoto 390-8621, Japan.ORCID 0000-0001-6789-5214
Xiaoran CuiDepartment of Aging Biology, Institute of Pathogenesis and Disease Prevention, Shinshu University Graduate School of Medicine, Matsumoto 390-8621, Japan.ORCID 0000-0002-9231-5012
Yuichi IgarashiDepartment of Aging Biology, Institute of Pathogenesis and Disease Prevention, Shinshu University Graduate School of Medicine, Matsumoto 390-8621, Japan.ORCID 0000-0002-1459-1978
Jinko SawashitaSupplemental Nutrition Division, Pharma & Supplemental Nutrition Solutions Vehicle, Kaneka Corporation, Osaka 530-8288, Japan.ORCID 0000-0001-8016-6649
Masayuki MoriDepartment of Aging Biology, Institute of Pathogenesis and Disease Prevention, Shinshu University Graduate School of Medicine, Matsumoto 390-8621, Japan.ORCID 0000-0002-0113-8402
Keiichi HiguchiDepartment of Aging Biology, Institute of Pathogenesis and Disease Prevention, Shinshu University Graduate School of Medicine, Matsumoto 390-8621, Japan.ORCID 0000-0003-0482-9214
Shinshu University · JPHebei Medical University · CNKaneka (Japan) · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Amyloidosis is a group of diseases characterized by protein misfolding and aggregation to form amyloid fibrils and subsequent deposition within various tissues. Previous studies have indicated that amyloidosis is often associated with oxidative stress. However, it is not clear whether oxidative stress is involved in the progression of amyloidosis. We administered the oxidative stress inhibitors tempol and apocynin via drinking water to the R1.P1-

Indexed as

AmyloidosisAnimalsApolipoprotein A-IIDietary SupplementsDisease ProgressionFemaleMiceOxidative Stressamyloidogenic apolipoprotein A-II, mouseApolipoprotein A-II

Identifiers

PMID31281565
PMCPMC6589291
OpenAlexW2948348737

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.