Evidence map›Paper›PMID 31281517›Full record

ArticleTheranostics2019

Suppression of YAP/TAZ-Notch1-NICD axis by bromodomain and extraterminal protein inhibition impairs liver regeneration.

Chen Liu, Xiawei Cheng, Juntao Chen, Yao Wang, Xiaoying Wu, Rui Tian, Baoqing Liu, Xianfeng Ding, Qiming Sun, Weihua Gong

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.4field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 28 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Chen LiuDepartment of Surgery, Second Affiliated Hospital of School of Medicine, Zhejiang University, Hangzhou 310058, China.
Xiawei ChengDepartment of Biochemistry, and Department of Cardiology of Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310058, China.
Juntao ChenDepartment of Surgery, Second Affiliated Hospital of School of Medicine, Zhejiang University, Hangzhou 310058, China.
Yao WangCollege of Life Sciences and Medicine, Zhejiang Sci-Tech University, Hangzhou 310018, China.
Xiaoying WuDepartment of Thyroid and Breast Surgery, Tongde Hospital of Zhejiang Province, Hangzhou, 310000, China.
Rui TianDepartment of Biochemistry, and Department of Cardiology of Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310058, China.
Baoqing LiuDepartment of Surgery, Second Affiliated Hospital of School of Medicine, Zhejiang University, Hangzhou 310058, China.
Xianfeng DingCollege of Life Sciences and Medicine, Zhejiang Sci-Tech University, Hangzhou 310018, China.
Qiming SunDepartment of Biochemistry, and Department of Cardiology of Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310058, China.
Weihua GongDepartment of Surgery, Second Affiliated Hospital of School of Medicine, Zhejiang University, Hangzhou 310058, China.
Second Affiliated Hospital of Zhejiang University · CNZhejiang Sci-Tech University · CNTongde Hospital of Zhejiang Province · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Liver RegenerationSignal TransductionAdaptor Proteins, Signal TransducingAnimalsCell Cycle ProteinsCell ProliferationDown-RegulationHepatectomyHepatocytesLiverMaleMice, Inbred C57BLNerve Tissue ProteinsProtein DomainsReceptor, Notch1Receptors, Cell SurfaceAdaptor Proteins, Signal TransducingCell Cycle ProteinsDner protein, mouseNerve Tissue ProteinsReceptor, Notch1Receptors, Cell SurfaceTrans-ActivatorsWwtr1 protein, mouseYap1 protein, mouseYAP-Signaling ProteinsBET proteinsliver regenerationNotch signaling pathwayYAP/TAZ

Identifiers

PMID31281517
PMCPMC6587347
OpenAlexW2949620002

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.