Evidence map›Paper›PMID 31281486›Full record

ArticleTheranostics2019

Versatile and Finely Tuned Albumin Nanoplatform based on Click Chemistry.

Ji Yong Park, Myung Geun Song, Woo Hyoung Kim, Kyu Wan Kim, Nadeem Ahmed Lodhi, Jin Yeong Choi, Young Ju Kim, Jung Young Kim, Hyewon Chung, Chiwoo Oh and 7 more

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.6field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
  2. Optimization ofJournal of nanobiotechnology · 2026
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  3. Review
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  5. Article
  6. Article
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  8. Article
  9. Intrathecal [Scientific reports · 2023
    Article
  10. Article
  11. Review
  12. Nuclear medicine and molecular imaging · 2022
    Article
  13. Review
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 2 institutions in 1 country.

Ji Yong ParkDepartment of Nuclear Medicine, Seoul National University Hospital, College of Medicine, Seoul, South Korea.
Myung Geun SongDepartment of Nuclear Medicine, Seoul National University Hospital, College of Medicine, Seoul, South Korea.
Woo Hyoung KimDivision of Pharmaceuticals and Clinical Development, DawonMedax Co., Ltd., Seoul, South Korea.
Kyu Wan KimDepartment of Nuclear Medicine, Seoul National University Hospital, College of Medicine, Seoul, South Korea.
Nadeem Ahmed LodhiDepartment of Nuclear Medicine, Seoul National University Hospital, College of Medicine, Seoul, South Korea.
Jin Yeong ChoiGraduate School of Convergence Science and Technology, Seoul National University, Seoul, South Korea.
Young Ju KimDepartment of Nuclear Medicine, Seoul National University Hospital, College of Medicine, Seoul, South Korea.
Jung Young KimDepartment of RI Technology-Convergence, Korean Institute of Radiological & Medical Sciences (KIRAMS), Seoul, South Korea.
Hyewon ChungDepartment of Microbiology and Immunology, Institute of Endemic Disease, College of Medicine, Seoul National University, Seoul, South Korea.
Chiwoo OhGraduate School of Convergence Science and Technology, Seoul National University, Seoul, South Korea.
Yun-Sang LeeDepartment of Nuclear Medicine, Seoul National University Hospital, College of Medicine, Seoul, South Korea.
Keon Wook KangDepartment of Nuclear Medicine, Seoul National University Hospital, College of Medicine, Seoul, South Korea.
Hyung-Jun ImGraduate School of Convergence Science and Technology, Seoul National University, Seoul, South Korea.
Seung Hyeok SeokDepartment of Microbiology and Immunology, Institute of Endemic Disease, College of Medicine, Seoul National University, Seoul, South Korea.
Dong Soo LeeDepartment of Nuclear Medicine, Seoul National University Hospital, College of Medicine, Seoul, South Korea.
Edmund E KimDepartment of Nuclear Medicine, Seoul National University Hospital, College of Medicine, Seoul, South Korea.
Jae Min JeongDepartment of Nuclear Medicine, Seoul National University Hospital, College of Medicine, Seoul, South Korea.
Seoul National University · KRSeoul National University Hospital · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Albumin is one of the most attractive nanoplatforms for targeted imaging and drug delivery due to its biocompatibility and long circulation half-life. However, previously reported albumin-based nanoplatforms have shown inconsistent blood circulation half-life according to the modified methods, and the affecting factors were not well evaluated, which could hamper the clinical translation of albumin-based nanoplatforms. Herein, we developed a finely tuned click-chemistry based albumin nanoplatform (CAN) with a longer circulation half-life and an efficient tumor targeting ability.

Indexed as

AlbuminsDrug Delivery SystemsRadiopharmaceuticalsAnimalsClick ChemistryCopper RadioisotopesFolate Receptors, GPI-AnchoredFolic AcidHalf-LifeIsotope LabelingMiceNeoplasmsPositron-Emission TomographyRadiotherapyTheranostic NanomedicineTissue DistributionAlbuminsCopper-64Copper RadioisotopesFolate Receptors, GPI-AnchoredFolic AcidRadiopharmaceuticalsalbuminclick chemistrypositron emission tomographytheranostics

Identifiers

PMID31281486
PMCPMC6587158
OpenAlexW2947041654

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.