Evidence map›Paper›PMID 31281419›Full record

ArticleEcancermedicalscience2019

Primary cardiac angiosarcoma diagnosed in the first trimester of pregnancy.

Ethan A Burns, Amna Ahmed, Anusha Sunkara, Usman Khan, Roozbeh Sharif, Maen Abdelrahim, Michael Reardon, Barry Trachtenberg

Abstract readCase Reports
In one paragraph

Article in Ecancermedicalscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Perigraft hygroma mimicking recurrent angiosarcoma of the right atrium.General thoracic and cardiovascular surgery · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ethan A BurnsInternal Medicine, Houston Methodist Hospital, Houston, TX 77030, USA.
Amna AhmedInternal Medicine, Houston Methodist Hospital, Houston, TX 77030, USA.
Anusha SunkaraHouston Methodist DeBakey Heart and Vascular Center, Houston, TX 77030, USA.
Usman KhanHouston Methodist Cancer Center, Houston, TX 77030, USA.
Roozbeh SharifHouston Methodist Critical Care, Houston, TX 77030, USA.
Maen AbdelrahimHouston Methodist Cancer Center, Houston, TX 77030, USA.
Michael ReardonHouston Methodist DeBakey Heart and Vascular Center, Houston, TX 77030, USA.
Barry TrachtenbergHouston Methodist DeBakey Heart and Vascular Center, Houston, TX 77030, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Primary cardiac angiosarcoma (PCAS) is a malignancy seldom seen in pregnancy. A 23-year-old G1P0 Chinese female was found to have PCAS during her first trimester when she presented with tamponade physiology. The transthoracic echocardiography (TTE) results did not indicate the presence of an intracardiac lesion, and pericardial fluid cytology analysis showed no evidence of malignancy. Cardiac magnetic resonance imaging (CMRI) exhibited a right atrial mass, and tissue biopsy indicated a high-grade angiosarcoma. MRI of the abdomen was suggestive of liver metastasis. She underwent an abortion and was started on combination chemotherapy, with a reduction in both the cardiac and liver masses. In cardiac angiosarcomas, advanced imaging modalities such as MRI should be utilised when there is high clinical suspicion or in the case of pregnancy when trying to minimise foetal harm. Prognosis is poor, and a standardised treatment protocol regardless of pregnancy continues to elude the medical community.

Indexed as

cardiac magnetic resonance imagingchemotherapyechocardiographypericardial tamponadepregnancyprimary cardiac angiosarcoma

Identifiers

PMID31281419
PMCPMC6546259

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.