Evidence map›Paper›PMID 31281264›Full record

ReviewFrontiers in physiology2019

Essential Oils as Stress-Reducing Agents for Fish Aquaculture: A Review.

Carine de Freitas Souza, Matheus Dellaméa Baldissera, Bernardo Baldisserotto, Berta Maria Heinzmann, Juan Antonio Martos-Sitcha, Juan Miguel Mancera

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in physiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
6.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 189 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. ACS chemical neuroscience · 2025
    Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Antibacterial and Antibiofilm Activity of Essential Oils AgainstAnimals : an open access journal from MDPI · 2024
    Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Carine de Freitas SouzaDepartment of Physiology and Pharmacology, Universidade Federal de Santa Maria, Santa Maria, Brazil.
Matheus Dellaméa BaldisseraDepartment of Microbiology and Parasitology, Universidade Federal de Santa Maria, Santa Maria, Brazil.
Bernardo BaldisserottoDepartment of Physiology and Pharmacology, Universidade Federal de Santa Maria, Santa Maria, Brazil.
Berta Maria HeinzmannDepartment of Industrial Pharmacy, Universidade Federal de Santa Maria, Santa Maria, Brazil.
Juan Antonio Martos-SitchaDepartment of Biology, Faculty of Marine and Environmental Sciences, Instituto Universitario de Investigación Marina, Campus de Excelencia Internacional del Mar, University of Cádiz, Cádiz, Spain.
Juan Miguel ManceraDepartment of Biology, Faculty of Marine and Environmental Sciences, Instituto Universitario de Investigación Marina, Campus de Excelencia Internacional del Mar, University of Cádiz, Cádiz, Spain.
Universidade Federal de Santa Maria · BRUniversidad de Cádiz · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In fish, stressful events initiate a hormone cascade along the hypothalamus-pituitary-interrenal and hypothalamus-sympathetic-chromaffin (HSC) axis to evoke several physiological reactions in order to orchestrate and maintain homeostasis. Several biotic and abiotic factors, as well as aquaculture procedures (handling, transport, or stocking density), activated stress system inducing negative effects on different physiological processes in fish (growth, reproduction, and immunity). In order to reduce these consequences, the use of essential oils (EOs) derived from plants has been the focus of aquaculture studies due to their diverse properties (e.g., anesthetic, antioxidant, and antimicrobial), which have been shown to reduce biochemical and endocrine alterations and, consequently, to improve the welfare status. Recently, several studies have shown that biogenic compounds isolated from different EOs present excellent biological activities, as well as the nanoencapsulated form of these EOs may potentiate their effects. Overall, EOs presented less side effects than synthetic compounds, but their stress-reducing efficacy is related to their chemical composition, concentration or chemotype used. In addition, their species-specific actions must be clearly established since they can act as stressors by themselves if their concentrations and chemotypes used are not suitable. For this reason, it is necessary to assess the effect of these natural compound mixtures in different fish species, from marine to freshwater, in order to find the ideal concentration range and the way for their administration to obtain the desired biological activity, without any undesired side effects. In this review, the main findings regarding the use of different EOs as stress reducers will be presented to highlight the most important issues related to their use to improve fish welfare in aquaculture.

Indexed as

aquaculturefish healthfish immundogyfish stressnatural compounds

Identifiers

PMID31281264
PMCPMC6596282
OpenAlexW2952826858

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.