Evidence map›Paper›PMID 31281244›Full record

ArticleFrontiers in cellular neuroscience2019

The Modulation of Gamma Oscillations by Methamphetamine in Rat Hippocampal Slices.

Yanan Li, Xin'e Xie, Hang Xing, Xiang Yuan, Yuan Wang, Yikai Jin, Jiangang Wang, Martin Vreugdenhil, Ying Zhao, Ruiling Zhang and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Yanan LiThe Second Affiliated Hospital, Xinxiang Medical University, Xinxiang, China.
Xin'e XieKey Laboratory for the Brain Research of Henan Province, Department of Physiology, Xinxiang Medical University, Xinxiang, China.
Hang XingKey Laboratory for the Brain Research of Henan Province, Department of Physiology, Xinxiang Medical University, Xinxiang, China.
Xiang YuanThe First Affiliated Hospital, College of Clinical Medicine, Henan University of Science and Technology, Luoyang, China.
Yuan WangKey Laboratory for the Brain Research of Henan Province, Department of Physiology, Xinxiang Medical University, Xinxiang, China.
Yikai JinKey Laboratory for the Brain Research of Henan Province, Department of Physiology, Xinxiang Medical University, Xinxiang, China.
Jiangang WangKey Laboratory for the Brain Research of Henan Province, Department of Physiology, Xinxiang Medical University, Xinxiang, China.
Martin VreugdenhilDepartment of Health Sciences, Birmingham City University, Birmingham, United Kingdom.
Ying ZhaoKey Laboratory of Clinical Psychopharmacology, School of Pharmacy, Xinxiang Medical University, Xinxiang, China.
Ruiling ZhangThe Second Affiliated Hospital, Xinxiang Medical University, Xinxiang, China.
Chengbiao LuThe Second Affiliated Hospital, Xinxiang Medical University, Xinxiang, China.
Xinxiang Medical University · CNHenan Psychiatric Hospital · CNBirmingham City University · GBFirst Affiliated Hospital of Henan University of Science and Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gamma frequency oscillations (γ, 30-100 Hz) have been suggested to underlie various cognitive and motor functions. The psychotomimetic drug methamphetamine (MA) enhances brain γ oscillations associated with changes in psychomotor state. Little is known about the cellular mechanisms of MA modulation on γ oscillations. We explored the effects of multiple intracellular kinases on MA modulation of γ induced by kainate in area CA3 of rat ventral hippocampal slices. We found that dopamine receptor type 1 and 2 (DR1 and DR2) antagonists, the serine/threonine kinase PKB/Akt inhibitor and

Indexed as

Akt/PKBDRhippocampusmethamphetamineNMDARγ oscillation

Identifiers

PMID31281244
PMCPMC6598082
OpenAlexW2951430725

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.