Evidence map›Paper›PMID 31281243›Full record

ArticleFrontiers in cellular neuroscience2019

Interferon Regulatory Factor 3 Deficiency Induces Age-Related Alterations of the Retina in Young and Old Mice.

Xi Zhang, Jingyi Zhu, Xianjun Chen, Zhang Jie-Qiong, Xue Li, Linlin Luo, Huang Huang, Wenyi Liu, Xinyuan Zhou, Jun Yan and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Insufficient Oligodendrocyte Turnover in Optic Nerve Contributes to Age-Related Axon Loss and Visual Deficits.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023
    Article
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Xi ZhangDepartment of Ophthalmology, Institute of Surgery Research, Army Medical Center of PLA (Daping Hospital), Army Medical University, Chongqing, China.
Jingyi ZhuDepartment of Ophthalmology, Institute of Surgery Research, Army Medical Center of PLA (Daping Hospital), Army Medical University, Chongqing, China.
Xianjun ChenDepartment of Histology and Embryology, Chongqing Key Laboratory of Neurobiology, Army Medical University, Chongqing, China.
Zhang Jie-QiongDepartment of Ophthalmology, Institute of Surgery Research, Army Medical Center of PLA (Daping Hospital), Army Medical University, Chongqing, China.
Xue LiDepartment of Ophthalmology, Institute of Surgery Research, Army Medical Center of PLA (Daping Hospital), Army Medical University, Chongqing, China.
Linlin LuoDepartment of Ophthalmology, Institute of Surgery Research, Army Medical Center of PLA (Daping Hospital), Army Medical University, Chongqing, China.
Huang HuangInstitute of Immunology, Army Medical University, Chongqing, China.
Wenyi LiuDepartment of Ophthalmology, Institute of Surgery Research, Army Medical Center of PLA (Daping Hospital), Army Medical University, Chongqing, China.
Xinyuan ZhouInstitute of Immunology, Army Medical University, Chongqing, China.
Jun YanDepartment of Ophthalmology, Institute of Surgery Research, Army Medical Center of PLA (Daping Hospital), Army Medical University, Chongqing, China.
Sen LinDepartment of Ophthalmology, Institute of Surgery Research, Army Medical Center of PLA (Daping Hospital), Army Medical University, Chongqing, China.
Jian YeDepartment of Ophthalmology, Institute of Surgery Research, Army Medical Center of PLA (Daping Hospital), Army Medical University, Chongqing, China.
Army Medical University · CNDaping Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Age-related changes in visual function and retina structure are very common in aged animals, but the underlying mechanisms of these changes remain unclear. Here we report that the expression of interferon regulatory factor 3 (

Indexed as

ERGIRF3retinaretinal thicknesssenescencesynaptic ectopia

Identifiers

PMID31281243
PMCPMC6596281
OpenAlexW2948362190

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.