Evidence map›Paper›PMID 31281093›Full record

ArticleCardiovascular revascularization medicine : including molecular interventions2020

Impact of BASILICA on Sinus and Neo-Sinus Hemodynamics after Valve-in-Valve with and without Coronary Flow.

Hoda Hatoum, Pablo Maureira, Scott Lilly, Lakshmi Prasad Dasi

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In one paragraph

Article in Cardiovascular revascularization medicine : including molecular interventions, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  3. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Hoda HatoumDepartment of Biomedical Engineering, The Ohio State University, Columbus, OH, USA.
Pablo MaureiraDepartment of Cardiovascular Surgery, CHU de Nancy, Nancy, France.
Scott LillyDivision of Cardiovascular Medicine, Department of Internal Medicine, The Ohio State University, Columbus, OH, USA.
Lakshmi Prasad DasiDepartment of Biomedical Engineering, The Ohio State University, Columbus, OH, USA. Electronic address: lakshmi.dasi@osumc.edu.

Funding

Superhydrophobic Heart Valve ProsthesisR01HL135505 · NHLBI · OHIO STATE UNIVERSITY · PI DASI, LAKSHMI PRASAD, KOTA, ARUN KUMAR · 2017 to 2020
$2.9M
Hyaluronan enhanced polymeric heart valve prosthesisR01HL119824 · NHLBI · OHIO STATE UNIVERSITY · PI DASI, LAKSHMI PRASAD · 2013 to 2017
$1.7M
Superomniphobic flow controlled prosthetic heart valveR21HL139208 · NHLBI · OHIO STATE UNIVERSITY · PI DASI, LAKSHMI PRASAD, KOTA, ARUN KUMAR · 2018 to 2019
$408k
Cost Effective Trileaflet BioPolymeric Heart Valve For IndiaR03EB014255 · NIBIB · OHIO STATE UNIVERSITY · PI DASI, LAKSHMI PRASAD, JAMES, SUSAN P · 2015 to 2016
$244k
NHLBI NIH HHS R01 HL119824NHLBI NIH HHS R01 HL135505NHLBI NIH HHS R21 HL139208NIBIB NIH HHS R03 EB014255
6 · The paper itself

Abstract

background/purposeThis study aims at evaluating the impact of BASILICA on neo-sinus and sinus hemodynamics with and without coronary flow. Leaflet thrombosis after valve-in-valve (ViV) may compromise not only leaflet mobility but also affect valve durability and performance. METHODS/MATERIALS: In a 23 mm transparent surgical aortic valve model, a 23 mm Edwards SAPIEN 3 and a 26 mm Medtronic Evolut were deployed before and after leaflet laceration, in models with and without coronary flow. Neo-sinus and sinus hemodynamics were evaluated in the aortic position of a pulse duplicator and particle image velocimetry was performed in order to quantify sinus flow hemodynamics along with sinus and neo-sinus washout.

resultsBASILICA-type leaflet laceration procedure led to (a) an increase in the velocities in the sinus and the neo-sinus by 50% for Evolut ViV with and without coronary flow, 70% for non-coronary SAPIEN 3 ViV and 10% for coronary SAPIEN 3 ViV, and (b) an improvement in overall washout up to 2 cycles in the neo-sinus and 0.5 cycles in the sinus.

conclusionsA BASILICA-type leaflet laceration approach may improve sinus and neo-sinus hemodynamics through decreasing flow stasis and enabling less confined blood flow. BASILICA confers coronary sinus flow patterns to the non-coronary sinus.

Indexed as

Coronary CirculationHeart Valve ProsthesisHemodynamicsAortic ValveBlood Flow VelocityCoronary SinusHeart Valve Prosthesis ImplantationHumansMaterials TestingProsthesis DesignTime FactorsBASILICALacerationLeaflet thrombosisTAVRValve-in-valveWashout

Identifiers

PMID31281093
PMCPMC6935435

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.