ArticleHypertension (Dallas, Tex. : 1979)2019
High Salt Activates CD11c
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Article in Hypertension (Dallas, Tex. : 1979), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 101 papers.
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101citing papers in PubMed
10.1field-weighted citation impact, top 1% of its field
What it found
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Who cites it
101 citing papers in PubMed, 138 citations in OpenAlex.
- Gene-environment interaction modifies the association between hyperinsulinemia and serum urate levels through SLC22A12.The Journal of clinical investigation · 2025Trial
- White Blood Cells and Blood Pressure: A Mendelian Randomization Study.Circulation · 2020Trial
- Gut dysbiosis, blood pressure regulation, and cardiometabolic risk in polyendocrine metabolic ovarian syndrome (PMOS).Reviews in endocrine & metabolic disorders · 2026Review
- High-Salt Diet Exacerbates Murine Imiquimod-Induced Psoriasis-like Dermatitis via Activation of Serum- and Glucocorticoid-Inducible Kinase 1.International journal of molecular sciences · 2026Article
- Serum/glucocorticoid-regulated kinase 1 regulates vascular inflammation in atherosclerosis.Acta pharmacologica Sinica · 2026Article
- Salt and chronic kidney disease.Nature reviews. Nephrology · 2026Review
- Pathophysiology and Clinical Relevance of Microvascular Remodeling in Arterial Hypertension.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2026Review
- The impact of inflammation, neuromodulation, and gut microbiota on developing cardiac fibrosis and hypertension.Cardiovascular research · 2026Review
- A sodium-HIF1α axis coordinates immune metabolic reprogramming and mitochondrial remodeling in salt-sensitive hypertension.Research square · 2026Article
- Hypertension-Induced Renal Injury: From Pathophysiology to Therapeutic Perspectives.Biomedicines · 2026Review
- Recent Advances in Dual COX/LOX Inhibitor Design (2020-2024): Establishing "Life (Basel, Switzerland) · 2026Review
- The SGK1/ENaC axis in renal injury during salt-sensitive hypertension: from sodium sensing to inflammation.Frontiers in immunology · 2026Review
- Blood pressure reduction and anti-inflammatory macrophage augmentation attenuate uterine immune dysregulation and inflammation in mice with salt-sensitive hypertension.Clinical science (London, England : 1979) · 2025Article
- Immunology of Hypertension: Pathophysiological and Therapeutic Aspects.International journal of molecular sciences · 2025Review
- Salt sensitivity of blood pressure: mechanisms and sex-specific differences.Nature reviews. Cardiology · 2025Review
- Uncovering immune pathways for therapeutic targeting of hypertension.Expert opinion on therapeutic targets · 2025Review
- Poricoic Acid A Protects Against High-Salt-Diet Induced Renal Fibrosis by Modulating Gut Microbiota and SCFA Metabolism.Plant foods for human nutrition (Dordrecht, Netherlands) · 2025Article
- Dietary salt, vascular dysfunction, and cognitive impairment.Cardiovascular research · 2025Review
- Aryl Hydrocarbon Receptor Activation Promotes Effector CD4+ T Cell Homeostasis and Restrains Salt-Sensitive Hypertension.Function (Oxford, England) · 2025Article
- Recent advances on immunity and hypertension: the new cells on the kidney block.American journal of physiology. Renal physiology · 2025Review
41 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
10 authors at 3 institutions in 1 country.
Justin P Van BeusecumFrom the Division of Clinical Pharmacology, Department of Medicine (J.P.V.B., N.R.B., L.A.A., L.X., H.A.I., D.G.H., A.K.), Vanderbilt University Medical Center, Nashville, TN.
Natalia R BarbaroFrom the Division of Clinical Pharmacology, Department of Medicine (J.P.V.B., N.R.B., L.A.A., L.X., H.A.I., D.G.H., A.K.), Vanderbilt University Medical Center, Nashville, TN.
Zoe McDowellSchool of Graduate Studies and Research, Meharry Medical College, Nashville, TN (Z.M.).
Luul A AdenFrom the Division of Clinical Pharmacology, Department of Medicine (J.P.V.B., N.R.B., L.A.A., L.X., H.A.I., D.G.H., A.K.), Vanderbilt University Medical Center, Nashville, TN.
Liang XiaoFrom the Division of Clinical Pharmacology, Department of Medicine (J.P.V.B., N.R.B., L.A.A., L.X., H.A.I., D.G.H., A.K.), Vanderbilt University Medical Center, Nashville, TN.
Arvind K PandeyDivision of Cardiology, Department of Medicine (A.K.P.), Vanderbilt University Medical Center, Nashville, TN.
Hana A ItaniFrom the Division of Clinical Pharmacology, Department of Medicine (J.P.V.B., N.R.B., L.A.A., L.X., H.A.I., D.G.H., A.K.), Vanderbilt University Medical Center, Nashville, TN.
Lauren E HimmelPharmacology and Toxicology, Faculty of Medicine, American University of Beirut, and Division of Comparative Medicine, Department of Pathology, Microbiology and Immunology (L.E.H.), Vanderbilt University Medical Center, Nashville, TN.
David G HarrisonFrom the Division of Clinical Pharmacology, Department of Medicine (J.P.V.B., N.R.B., L.A.A., L.X., H.A.I., D.G.H., A.K.), Vanderbilt University Medical Center, Nashville, TN.
Annet KiraboFrom the Division of Clinical Pharmacology, Department of Medicine (J.P.V.B., N.R.B., L.A.A., L.X., H.A.I., D.G.H., A.K.), Vanderbilt University Medical Center, Nashville, TN.
Vanderbilt University Medical Center · USAmerican University · USMeharry Medical College · US
Funding
Tumor Immunology and Microenvironment Research ProgramP30CA068485 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI MATTHEW J TYSKA · 1995 to 2026
$172.8MVanderbilt Institute for Clinical and Translational Research (VICTR) -Identifying correlates of functional immunity in SARS-CoV-2 convalescent plasmaUL1TR002243 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Paul A. Harris, Wesley H Self · 2017 to 2026
$130.7MVanderbilt Mouse Metabolic Physiology CenterU24DK059637 · NIDDK · VANDERBILT UNIVERSITY · PI WASSERMAN, DAVID H · 2001 to 2015
$14.9MVanderbilt Mouse Metabolic Phenotyping CenterU2CDK059637 · NIDDK · VANDERBILT UNIVERSITY · PI WASSERMAN, DAVID H · 2016 to 2021
$6.3MMechanisms of Immune Activation in HypertensionR35HL140016 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI HARRISON, DAVID G · 2018 to 2024
$5.3MRole of Salt, Isoketal-modified Proteins and Dendritic Cells in HypertensionK01HL130497 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI KIRABO, ANNET · 2016 to 2020
$803kThe role of salt and SGK1 on NADPH oxidase stabilization in dendritic cells in hypertensionF32HL143927 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI VAN BEUSECUM, JUSTIN PIETER · 2019 to 2020
$120kNCATS NIH HHS UL1 TR002243NCI NIH HHS P30 CA068485NHLBI NIH HHS F32 HL143927NHLBI NIH HHS K01 HL130497NHLBI NIH HHS R35 HL140016NIDDK NIH HHS U24 DK059637NIDDK NIH HHS U2C DK059637
Abstract
Salt-sensing mechanisms in hypertension involving the kidney, vasculature, and central nervous system have been well studied; however, recent studies suggest that immune cells can sense sodium (Na
Indexed as
Analysis of VarianceAnimalsAntigen-Presenting CellsCD11c AntigenCells, CulturedDisease Models, AnimalFlow CytometryHypertensionImmunoblottingMaleMiceMice, Inbred C57BLNephritisNG-Nitroarginine Methyl EsterProtein Serine-Threonine KinasesRandom AllocationCD11c AntigenNG-Nitroarginine Methyl EsterProtein Serine-Threonine KinasesSodium ChlorideSodium Chloride, Dietarycytokinesdendritic cellsinflammationkidney
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.