Evidence map›Paper›PMID 31280351›Full record

ArticleInternational journal of colorectal disease2019

Relationships between the results of anorectal investigations and symptom severity in patients with faecal incontinence.

P T Heitmann, P Rabbitt, A Schloithe, V Patton, P P Skuza, D A Wattchow, P G Dinning

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Article in International journal of colorectal disease, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

P T HeitmannCollege of Medicine and Public Health & Centre for Neuroscience, Flinders University, Adelaide, SA, Australia.
P RabbittDepartments of Surgery and Gastroenterology, Flinders Medical Centre, Flinders Drive, Bedford Park, SA, 5042, Australia.
A SchloitheCollege of Medicine and Public Health & Centre for Neuroscience, Flinders University, Adelaide, SA, Australia.
V PattonCentre for Nursing Research, Edith Cowan University/Sir Charles Gairdner Hospital, Nedlands, Western Australia.
P P SkuzaCentral Library, Flinders University, Bedford Park, South Australia.
D A WattchowCollege of Medicine and Public Health & Centre for Neuroscience, Flinders University, Adelaide, SA, Australia.
P G DinningCollege of Medicine and Public Health & Centre for Neuroscience, Flinders University, Adelaide, SA, Australia. phil.dinning@flinders.edu.au.ORCID http://orcid.org/0000-0001-8910-2801

Funding

Colorectal Surgical Society of Australia and New Zealand (CSSANZ) Foundation PhD Scholarship
6 · The paper itself

Abstract

purposeAnorectal dysfunction is the focus of diagnostic investigations for faecal incontinence. However, severity of incontinence and anorectal investigation results can be discordant. The aim of this study was to define the relationships between anorectal investigation results and incontinence severity to determine which measures, if any, were predictive of incontinence severity.

methodsPatients presenting for investigation of faecal incontinence completed a symptom questionnaire, anorectal manometry, rectal sensation, pudendal nerve terminal motor latency, and endoanal ultrasound. Bivariate analyses were conducted between the Jorge-Wexner score and investigation results. Subgroup analyses were performed for gender and symptom subtypes (urge, passive, mixed). A multiple regression analysis was performed.

resultsFive hundred and thirty-eight patients were included. There were weak correlations between the Jorge-Wexner score and maximal squeeze pressure [r = - 0.24, 95%CI(- 0.31, - 0.16), p < 0.001], and resting pressure [r = - 0.18, (95%CI(- 0.26, - 0.10), p < 0.001]. In men only, there were significant associations between the Jorge-Wexner score and endoanal sonography [IAS defects: t(113) = - 2.26, p = 0.03, d = 0.58, 95%CI(- 4.38, - 0.29)] and rectal sensation (MTV: r

conclusionAnorectal investigations cannot predict the severity of faecal incontinence. This may be due to limitations of diagnostic modalities, the heterogeneity of anorectal dysfunction in these patients, or contributing factors which are extrinsic to the anorectum.

Indexed as

AdolescentAdultAgedAged, 80 and overAnal CanalFecal IncontinenceFemaleHumansMaleMiddle AgedRectumRegression AnalysisSeverity of Illness IndexYoung AdultAnal canalDigestive system diseasesEndosonographyFaecal incontinenceManometryRectum

Identifiers

PMID31280351

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.