ArticleEuropean heart journal. Cardiovascular Imaging2020
Multicentre reference values for cardiac magnetic resonance imaging derived ventricular size and function for children aged 0-18 years.
Article in European heart journal. Cardiovascular Imaging, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 52 papers, 3 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
52 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Society for Cardiovascular Magnetic Resonance reference values ("normal values") in cardiovascular magnetic resonance: 2025 update.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2025Guideline
- Age-, body surface area-, and sex-specific reference values for cardiovascular magnetic resonance imaging derived ventricular and atrial size and function for Chinese healthy children.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2025Pooled it
- Multi-Organ Phenotypes of Offspring Born Following Hypertensive Disorders of Pregnancy: A Systematic Review.Journal of the American Heart Association · 2024Pooled it
- A preconception lifestyle intervention in women with obesity and cardiovascular health in their children.Pediatric research · 2023Trial
- Evaluation of Right Ventricular Size Metrics Measured with Cardiac Magnetic Resonance Imaging in Patients with Pulmonary Regurgitation.Pediatric cardiology · 2026Article
- The Clinical Role of Electrocardiographic Morphology of Premature Ventricular Contractions for Prognostic Outcomes in Children.Medicina (Kaunas, Lithuania) · 2026Observational
- Cone Reconstruction for Ebstein Anomaly: Effect on Tricuspid Valve Growth and Biventricular Remodelling in Children.Interdisciplinary cardiovascular and thoracic surgery · 2026Article
- Development and multicentre validation of an artificial intelligence electrocardiogram model for ventricular remodeling in repaired tetralogy of Fallot.European heart journal. Digital health · 2026Article
- Heart failure in a 10-year-old girl: incidental discovery of adrenal adenoma by cardiac MRI-case report.European heart journal. Case reports · 2026Article
- Echocardiographic Z-Score to Predict Pulmonary-Systemic Flow Ratio in Children With Atrial Septal Defect.Circulation reports · 2025Article
- Magnetic resonance imaging of pulmonary hypertension.Pediatric radiology · 2025Review
- Role of tricuspid valve repair in pulmonary atresia with intact ventricular septum: fresh autologous pericardium as a viable option.Interdisciplinary cardiovascular and thoracic surgery · 2025Article
- Predictors of Ventricular Abnormalities in Children with Idiopathic Ventricular Extrasystoles.Children (Basel, Switzerland) · 2025Article
- Cardiac remodeling and exercise tolerance in small for gestational age: a follow-up cohort study from preadolescence into adolescence.Frontiers in cardiovascular medicine · 2025Article
- Cardiovascular magnetic resonance 4D flow derived aortic and pulmonary wall shear stress in pediatric patients with repaired tetralogy of Fallot.Frontiers in pediatrics · 2025Article
- Case Report: Hemodynamic consequences of severe supraventricular arrhythmia assessed by real-time magnetic resonance imaging in combination with electrocardiography.Frontiers in cardiovascular medicine · 2025Article
- Cardiovascular magnetic resonance semi-automated threshold-based post-processing of right ventricular volumes in repaired tetralogy of Fallot.La Radiologia medica · 2024Article
- Article
- Accelerated cardiac magnetic resonance imaging using deep learning for volumetric assessment in children.Pediatric radiology · 2024Article
- The changing morphology of the ventricular walls of mouse and human with increasing gestation.Journal of anatomy · 2024Article
Corrections and comments
- Erratum issued
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimsCardiovascular magnetic resonance (CMR) imaging is an important tool in the assessment of paediatric cardiac disease. Reported reference values of ventricular volumes and masses in the paediatric population are based on small cohorts and several methodologic differences between studies exist. We sought to create steady-state free precession (SSFP) CMR reference values for biventricular volumes and mass by combining data of previously published studies and re-analysing these data in a standardized manner. METHODS AND
resultsA total of 141 healthy children (68 boys) from three European centres underwent cine-SSFP CMR imaging. Cardiac structures were manually contoured for end-diastolic and end-systolic phases in the short-axis orientation according to current standardized CMR post-processing guidelines. Volumes and masses were derived from these contours. Age-related reference curves were constructed using the lambda mu sigma method. Median age was 12.7 years (range 0.6-18.5). We report biventricular volumes and masses, unindexed and indexed for body surface area, stratified by age groups. In general, boys had approximately 15% higher biventricular volumes and masses compared with girls. Only in children aged <6 years old no gender differences could be observed. Left ventricle ejection fraction was slightly higher in boys in this study population (median 67% vs. 65%, P = 0.016). Age-related reference curves showed non-linear relations between age and cardiac parameters.
conclusionWe report volumetric SSFP CMR imaging reference values for children aged 0-18 years old in a relatively large multi-centre cohort. These references can be used in the follow-up of paediatric cardiac disease and for research purposes.
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