Evidence map›Paper›PMID 31280189›Full record

ReviewIn vivo (Athens, Greece)

Plasma Medicine: A Field of Applied Redox Biology.

Thomas VON Woedtke, Anke Schmidt, Sander Bekeschus, Kristian Wende, Klaus-Dieter Weltmann

Registry-linked trialOpen access · diamondAbstract readReview
In one paragraph

Review in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04886323 (Effect of Cold Atmospheric Plasma on Malassezia Folliculitis), which is not on this map. Cited by 123 papers.

0numbers the graph read from it
0cells of the map it votes in
123citing papers in PubMed
25.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04886323 nacompletednot on this map

Effect of Cold Atmospheric Plasma on Malassezia Folliculitis: a Randomized Controlled Trial

TypeinterventionalSponsorThe Second Hospital of Anhui Medical UniversityRan2022 to 2023Enrolled50ConditionsMalassezia FolliculitisArmsCold atmospheric plasma treatment device, Itraconazole Capsules
3 · Its place in the literature

Who cites it

123 citing papers in PubMed, 304 citations in OpenAlex.

  1. Trial
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  13. Penetration depth of cold atmospheric plasma into biological tissue: a review.Frontiers in bioengineering and biotechnology · 2026
    Review
  14. Article
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63 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Thomas VON WoedtkeLeibniz Institute for Plasma Science and Technology, INP Greifswald, Greifswald, Germany woedtke@inp-greifswald.de.
Anke SchmidtLeibniz Institute for Plasma Science and Technology, INP Greifswald, Greifswald, Germany.
Sander BekeschusZIK plasmatis at INP Greifswald, Greifswald, Germany.
Kristian WendeZIK plasmatis at INP Greifswald, Greifswald, Germany.
Klaus-Dieter WeltmannLeibniz Institute for Plasma Science and Technology, INP Greifswald, Greifswald, Germany.
Leibniz Institute for Plasma Science and Technology · DEUniversitätsmedizin Greifswald · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Plasma medicine comprises the application of physical plasma directly on or in the human body for therapeutic purposes. Three most important basic plasma effects are relevant for medical applications: i) inactivation of a broad spectrum of microorganisms, including multidrug-resistant pathogens, ii) stimulation of cell proliferation and angiogenesis with lower plasma treatment intensity, and iii) inactivation of cells by initialization of cell death with higher plasma treatment intensity, above all in cancer cells. Based on own published results as well as on monitoring of relevant literature the aim of this topical review is to summarize the state of the art in plasma medicine and connect it to redox biology. One of the most important results of basic research in plasma medicine is the insight that biological plasma effects are mainly mediated via reactive oxygen and nitrogen species influencing cellular redox-regulated processes. Plasma medicine can be considered a field of applied redox biology.

Indexed as

MedicinePlasma GasesAnimalsHumansOxidation-ReductionWound HealingPlasma Gasescold atmospheric plasma (CAP)Plasma medicineredox biologyreview

Identifiers

PMID31280189
PMCPMC6689367
OpenAlexW2954011306

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.