Evidence map›Paper›PMID 31280104›Full record

ArticleApplied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine2019

Automated production of a sphingosine-1 phosphate receptor 1 (S1P1) PET radiopharmaceutical [

Zonghua Luo, Jiwei Gu, Robert C Dennett, Gregory G Gaehle, Joel S Perlmutter, Delphine L Chen, Tammie L S Benzinger, Zhude Tu

Abstract read
In one paragraph

Article in Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Evaluation of [AJNR. American journal of neuroradiology · 2026
    Article
  2. Review
  3. Automated production of radiotracer [Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine · 2025
    Article
  4. Article
  5. Review
  6. Article
  7. Phase 1 Evaluation ofJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2022
    Article
  8. Article
  9. Review
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Zonghua LuoDepartment of Radiology, Washington University School of Medicine, St. Louis, MO, 63110, USA.
Jiwei GuDepartment of Radiology, Washington University School of Medicine, St. Louis, MO, 63110, USA.
Robert C DennettDepartment of Radiology, Washington University School of Medicine, St. Louis, MO, 63110, USA.
Gregory G GaehleDepartment of Radiology, Washington University School of Medicine, St. Louis, MO, 63110, USA.
Joel S PerlmutterDepartment of Radiology, Washington University School of Medicine, St. Louis, MO, 63110, USA; Department of Neurology, Neuroscience, Physical Therapy and Occupational Therapy, Washington University School of Medicine, St. Louis, MO, 63110, USA.
Delphine L ChenDepartment of Radiology, Washington University School of Medicine, St. Louis, MO, 63110, USA.
Tammie L S BenzingerDepartment of Radiology, Washington University School of Medicine, St. Louis, MO, 63110, USA.
Zhude TuDepartment of Radiology, Washington University School of Medicine, St. Louis, MO, 63110, USA. Electronic address: tuz@mir.wustl.edu.

Funding

Training/DisseminationP41EB025815 · NIBIB · WASHINGTON UNIVERSITY · PI Buck E. Rogers · 2018 to 2026
$12.7M
INVESTIGATIONS OF DEMENTIA IN PARKINSON DISEASER01NS075321 · NINDS · WASHINGTON UNIVERSITY · PI CAMPBELL, MEGHAN C, PERLMUTTER, JOEL SYNES · 2011 to 2021
$8.2M
PET SPHINGOSINE-1-PHOSPHATE RECEPTOR 1 (S1PR1) RADIOTRACERS FOR MULTIPLE SCLEROSISR01NS103988 · NINDS · WASHINGTON UNIVERSITY · PI Tammie Lee Smith Benzinger, Zhude Tu · 2017 to 2026
$5.3M
VALIDATION OF NEUROIMAGING BIOMARKERS FOR NIGROSTRIATAL NEURONSR01NS058714 · NINDS · WASHINGTON UNIVERSITY · PI PERLMUTTER, JOEL SYNES · 2008 to 2016
$4.4M
Quantification of Neuroinflammation inAlzheimer's Disease Using Diffusion BasisSpectrum ImagingR01AG054567 · NIA · WASHINGTON UNIVERSITY · PI BENZINGER, TAMMIE LEE SMITH, WANG, YONG · 2017 to 2021
$3.6M
Neuroinflammatory Biomarkers for Nigrostriatal InjuryR01NS107281 · NINDS · WASHINGTON UNIVERSITY · PI PERLMUTTER, JOEL SYNES · 2019 to 2023
$3.3M
IMAGING OPTIC NERVE FUNCTION AND PATHOLOGYU01EY025500 · NEI · WASHINGTON UNIVERSITY · PI SONG, SHENG-KWEI · 2015 to 2019
$3.1M
Neuroimaging of PDE10AR01NS103957 · NINDS · WASHINGTON UNIVERSITY · PI PERLMUTTER, JOEL SYNES, TU, ZHUDE · 2017 to 2021
$3.1M
Investigations of Dementia in Parkinson DiseaseRF1NS075321 · NINDS · WASHINGTON UNIVERSITY · PI CAMPBELL, MEGHAN C, PERLMUTTER, JOEL SYNES · 2023 to 2023
$2.3M
NEI NIH HHS U01 EY025500NIA NIH HHS R01 AG054567NIBIB NIH HHS P41 EB025815NINDS NIH HHS R01 NS058714NINDS NIH HHS R01 NS075321NINDS NIH HHS R01 NS103957NINDS NIH HHS R01 NS103988NINDS NIH HHS R01 NS107281NINDS NIH HHS R03 NS090269NINDS NIH HHS RF1 NS075321
6 · The paper itself

Abstract

Automated synthesis of a radiopharmaceutical 3-((2-fluoro-4-(5-(2'-methyl-2-(trifluoromethyl)-[1,1'-biphenyl]-4-yl)-1,2,4-oxadiazol-3-yl)benzyl) (methyl-

Indexed as

Positron-Emission TomographyAutomationCarbon RadioisotopesHumansQuality ControlRadiopharmaceuticalsSphingosine-1-Phosphate ReceptorsCarbon RadioisotopesRadiopharmaceuticalsSphingosine-1-Phosphate Receptors[(11)C]CS1P1AutomationPositron emission tomographyRadiopharmaceuticalSphingosine-1 phosphate receptor 1

Identifiers

PMID31280104
PMCPMC6708718

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.