Evidence map›Paper›PMID 31280093›Full record

ArticlePhytochemistry2019

Untargeted liquid chromatography coupled with mass spectrometry reveals metabolic changes in nitrogen-deficient Isatis indigotica Fortune.

Yi-Wen Cao, Ren-Jun Qu, Yu-Jing Miao, Xiao-Qing Tang, Ying Zhou, Lei Wang, Li Geng

Open access · bronzeAbstract read
In one paragraph

Article in Phytochemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Yi-Wen CaoCollege of Horticulture, Nanjing Agricultural University, Nanjing, 210095, China.
Ren-Jun QuCollege of Horticulture, Nanjing Agricultural University, Nanjing, 210095, China.
Yu-Jing MiaoCollege of Horticulture, Nanjing Agricultural University, Nanjing, 210095, China.
Xiao-Qing TangCollege of Horticulture, Nanjing Agricultural University, Nanjing, 210095, China. Electronic address: xqtang@njau.edu.cn.
Ying ZhouCollege of Horticulture, Nanjing Agricultural University, Nanjing, 210095, China.
Lei WangMaoshanXiancao Chinese Herbal Medicine Professional Cooperatives, Zhenjiang, 212400, China.
Li GengMaoshanXiancao Chinese Herbal Medicine Professional Cooperatives, Zhenjiang, 212400, China.
Nanjing Agricultural University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Isatis indigotica Fortune is a popular herb in traditional Chinese medicine, and various types of metabolites are the basis for its pharmacological efficacy. The biosynthesis and accumulation of these metabolites are closely linked to nitrogen availability; the benefits of low nitrogen application on the environment and herb quality are increasingly prominent. To analyze metabolic changes in the leaves and roots of I.indigotica in nitrogen deficiency conditions, and to identify the pathways and metabolites induced by low nitrogen availability, we used untargeted liquid chromatography coupled with mass spectrometry (UHPLC-TripleTOF) to obtain metabolomics profiling of I.indigotica under two N-deficiency treatments (0 kg/hm

Indexed as

MetabolomicsChromatography, LiquidIsatisMass SpectrometryNitrogenNitrogenDifferential metabolitesIsatis indigotica FortuneMetabolomicsNitrogen deficiencySecondary metabolism

Identifiers

PMID31280093
PMCPMC7111722
OpenAlexW2954181401

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.