ArticleJournal of affective disorders2019
Conceptualizing comorbid PTSD and depression among treatment-seeking, active duty military service members.
Article in Journal of affective disorders, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Prelimbic cortex-associated stress sensitisation and region-specific mitochondrial adaptations across preclinical approaches relevant to PTSD and depression.Neurobiology of stress · 2026Article
- Veteran and first responder family members show distinct mental health networks centered on negative emotions.Communications psychology · 2025Article
- Physiotherapy Within Inpatient Mental Health Wards: Involvement, Diagnoses, and Lifestyle Characteristics.Healthcare (Basel, Switzerland) · 2025Article
- Psychometric evaluation of the PCL-5: assessing validity, diagnostic utility, and bifactor structures.European journal of psychotraumatology · 2024Article
- Identifying depression in the United States veterans using deep learning algorithms, NHANES 2005-2018.BMC psychiatry · 2023Article
- The Posttraumatic Stress Disorder (PTSD) Checklist for DSM-5: A Systematic Review of Existing Psychometric Evidence.Clinical psychology : a publication of the Division of Clinical Psychology of the American Psychological Association · 2023Article
- Effects of intranasal (EClinicalMedicine · 2022Article
- Genetic evidence suggests posttraumatic stress disorder as a subtype of major depressive disorder.The Journal of clinical investigation · 2022Article
- Risk and protective factors for post-traumatic stress among New Zealand military personnel: A cross sectional study.PloS one · 2020Article
- A bidirectional examination of mental health symptoms and perceptions of leader support: Which comes first?Military psychology : the official journal of the Division of Military Psychology, American Psychological AssociationArticle
Corrections and comments
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Authors and funding
14 authors.
Funding
Abstract
backgroundAmong active duty service members and veterans with PTSD, depression is the most commonly diagnosed comorbid psychiatric condition. More research is warranted to investigate the relationship between PTSD and depression to improve treatment approaches. Byllesby et al. (2017) used confirmatory factor analyses in a sample of trauma-exposed combat veterans with PTSD and found that only the general distress factor, and not any specific symptom cluster of PTSD, predicted depression. This study seeks to replicate Byllesby et al. (2017) in a sample of treatment-seeking active duty soldiers.
methodsConfirmatory factor analyses, bifactor modeling, and structural equation modeling (SEM) were used with data gathered at pretreatment and posttreatment as part of a large randomized clinical trial.
resultsConfirmatory factor analyses and bifactor modeling demonstrated that PTSD symptom clusters, Negative Alterations in Cognition and Mood (NACM) and Alterations in Arousal and Reactivity (AAR), as well as the general distress factor significantly predicted depression at pretreatment and posttreatment. LIMITATIONS: The current study was predominantly male, limiting the generalizability to female service members with PTSD. Also, self-report measures were used, which may introduce response-bias.
conclusionsThe current study did not replicate Byllesby et al. (2017). Results demonstrated that the relationship between PTSD and depression among active duty service members can be explained by both transdiagnostic factors and disorder-specific symptoms.
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