ArticleHormones and behavior2019
Sex hormones and number processing. Progesterone and testosterone relate to hemispheric asymmetries during number comparison.
Article in Hormones and behavior, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Sex differences in brain homotopic co-activations: a meta-analytic study.Brain structure & function · 2022Pooled it
- Salt sensitivity of blood pressure: mechanisms and sex-specific differences.Nature reviews. Cardiology · 2025Review
- Does the Brain Care Which Direction We Read? A Cross-Cultural tDCS Study on Functional Lateralization of Number Processing.Brain and behavior · 2025Article
- Steroid hormones in fish, caution for present and future: A review.Toxicology reports · 2024Review
- Eye-movements during number comparison: Associations to sex and sex hormones.Physiology & behavior · 2020Article
- Dichotic listening performance and interhemispheric integration after stress exposure.Scientific reports · 2020Article
- Hemispheric Lateralization of Arithmetic Facts and Magnitude Processing for Two-Digit Numbers.Frontiers in human neuroscience · 2020Article
- Sex hormones and number processing. Progesterone and testosterone relate to hemispheric asymmetries during number comparison.Hormones and behavior · 2019Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
Like many visual stimuli, multi-digit numbers are of a hierarchical nature, with whole number magnitudes depending on individual digit magnitudes. Accordingly, multi-digit numbers can be processed in a holistic (whole number magnitudes) or decomposed manner (digit magnitudes). The compatibility effect during number comparison serves as an indicator of decomposed processing. It is characterized by impaired performance for items where the larger number contains the smaller unit-digit. We were recently able to demonstrate, that the compatibility effect indeed depends on an individual's tendency to process visual hierarchical stimuli on a global or local level. Accordingly, factors affecting global-local processing, should also affect number magnitude processing, i.e. the compatibility effect. Among these factors are hemispheric asymmetries, sex differences and sex hormones (estradiol, progesterone, testosterone). In the present study 39 men and 37 naturally cycling women in their luteal cycle phase completed a number comparison task with stimuli randomly presented to the left and right hemifield. As in previous studies, we observed a larger compatibility effect in the right hemifield (left hemisphere) than in the left hemifield (right hemisphere) and in men than in women. However, this is the first study to evaluate the effects of sex hormones on hemispheric asymmetries during number comparison. We found progesterone to relate to increased hemispheric asymmetries in men, but decreased hemispheric asymmetries in women. Additionally, testosterone was negatively related to hemispheric asymmetries in women's compatibility effect in reaction times. These results add to the growing evidence that sex hormones relate to hemispheric asymmetries in cognitive functions.
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