Evidence map›Paper›PMID 31279487›Full record

ReviewPlacenta2019

Volume and vascularity: Using ultrasound to unlock the secrets of the first trimester placenta.

S Mathewlynn, S L Collins

Abstract readReview
In one paragraph

Review in Placenta, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. First-trimester Placental Ultrasound (FirstPLUS) study: prediction of fetal growth restriction using OxNNet-derived first-trimester placental volume.Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology · 2026
    Observational
  3. Article
  4. Review
  5. Reference charts for first-trimester placental volume derived using OxNNet.Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology · 2025
    Observational
  6. Feto-placental blood vessel development.Development (Cambridge, England) · 2025
    Review
  7. Review
  8. Developments in functional imaging of the placenta.The British journal of radiology · 2023
    Review
  9. Observational
  10. Review
  11. Deep Learning strategies for Ultrasound in Pregnancy.European Medical Journal. Reproductive health · 2020
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

S MathewlynnDepartment of Obstetrics and Gynaecology, Milton Keynes University Hospital, Milton Keynes, UK.
S L CollinsNuffield Department of Women's and Reproductive Health, University of Oxford, UK; Fetal Medicine Unit, The Women's Centre, John Radcliffe Hospital, Oxford, UK. Electronic address: sally.collins@wrh.ox.ac.uk.

Funding

Development of real-time, automated 3D ultrasound tools for the study of placental invasion and morphologyU01HD087209 · NICHD · HACKENSACK UNIVERSITY MEDICAL CENTER · PI COLLINS, SALLY LOUISE, ZAMUDIO, STACY · 2015 to 2015
$3.3M
NICHD NIH HHS U01 HD087209
6 · The paper itself

Abstract

Fetal growth restriction (FGR) is a major cause of perinatal morbidity and mortality. Identifying which pregnancies are at risk of FGR facilitates enhanced surveillance and early delivery before fetal demise can ensue. However, existing risk stratification strategies yield an unacceptably low detection rate. A robust and reliable first trimester screening test for FGR would not only enable high-risk women to be appropriately monitored but would facilitate future trials for possible interventions to enhance fetal growth. Both the volume and vascularity of the first trimester placenta has been demonstrated to be linked to adverse pregnancy outcomes including FGR and pre-eclampsia. The investigation of novel ultrasound markers for FGR are discussed along with the development of methods for fully automatic placental volume estimation which has the potential for use as part of a multi-variable population-based screening test.

Indexed as

Pregnancy Trimester, FirstUltrasonography, PrenatalFemaleFetal DevelopmentHumansOrgan SizePlacentaPlacentationPregnancyFetal growth restrictionPlacental volumePower DopplerScreeningStillbirthUltrasound

Identifiers

PMID31279487
PMCPMC7586067

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.