Evidence map›Paper›PMID 31279455›Full record

ReviewMagnetic resonance imaging clinics of North America2019

Assessment of Cardiotoxicity of Cancer Chemotherapy: The Value of Cardiac MR Imaging.

Thiago Ferreira de Souza, Thiago Quinaglia, Tomas G Neilan, Otávio R Coelho-Filho

Abstract readReview
In one paragraph

Review in Magnetic resonance imaging clinics of North America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Review
  6. Cardiac MRI assessment of anthracycline-induced cardiotoxicity.Frontiers in cardiovascular medicine · 2022
    Review
  7. Review
  8. Article
  9. Multimodality Cardiac Imaging in the Era of Emerging Cancer Therapies.Journal of the American Heart Association · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Thiago Ferreira de SouzaFaculdade de Ciências Médicas - Universidade Estadual de Campinas, Rua Tessália Vieira de Camargo, 126, Campinas, São Paulo 13083-887, Brasil.
Thiago QuinagliaFaculdade de Ciências Médicas - Universidade Estadual de Campinas, Rua Tessália Vieira de Camargo, 126, Campinas, São Paulo 13083-887, Brasil.
Tomas G NeilanCardio-Oncology Program and Cardiac MR PET CT Program, Massachusetts General Hospital, Harvard Medical School, 55 Fruit Street, Boston, MA 02114, USA.
Otávio R Coelho-FilhoFaculdade de Ciências Médicas - Universidade Estadual de Campinas, Rua Tessália Vieira de Camargo, 126, Campinas, São Paulo 13083-887, Brasil; Division of Cardiology, Department of Medicine, State University of Campinas (UNICAMP), Rua Tessália Vieira de Camargo, 126, Campinas, São Paulo 13083-887, Brasil. Electronic address: orcfilho@unicamp.br.

Funding

The impact of HIV viral diversity and cellular immunity on HIV pathogenesisP30AI060354 · NIAID · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI ROBERT A. PARKER · 2004 to 2026
$94.4M
STOP-CA: Statins to prevent Cardiotoxicity from AnthracyclinesR01HL130539 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI NEILAN, TOMAS G, SCHERRER-CROSBIE, MARIELLE · 2016 to 2020
$3.2M
Mechanisms of Cardiac Dysfunction in HIV and the Effect of StatinsR01HL137562 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI NEILAN, TOMAS G, ZANNI, MARKELLA V. · 2017 to 2020
$2.7M
NHLBI NIH HHS K23 HL115260NHLBI NIH HHS R01 HL130539NHLBI NIH HHS R01 HL137562NIAID NIH HHS P30 AI060354
6 · The paper itself

Abstract

Chemotherapy is associated with cardiovascular injury, including the development of a cardiomyopathy and vascular remodeling. Cardiac magnetic resonance (CMR) is sensitive to detect not only established morphologic and functional abnormalities but also early, potentially reversible, signs of myocardial injury. It robustly detects and quantifies myocardial edema, inflammation, and focal fibrosis, as well as interstitial fibrosis and vascular remodeling. These capabilities support the role of CMR as an excellent tool for evaluating cardiotoxicity. Novel CMR markers may even enhance patient management by facilitating the early detection of reversible myocardial tissue remodeling before classic morphologic and functional changes appear.

Indexed as

CardiotoxicityHeartHumansMagnetic Resonance ImagingNeoplasmsCardiotoxicityCardiovascular magnetic resonanceChemotherapyMyocardial remodeling

Identifiers

PMID31279455
PMCPMC6624085

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.