ArticleBMC musculoskeletal disorders2019
Risk of joint replacement surgery in Taiwanese female adults with systemic lupus erythematosus: a population-based cohort study.
Article in BMC musculoskeletal disorders, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
6 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.
- A systematic review and meta-analysis comparing complications following total hip arthroplasty for systemic lupus erythematosus versus for non-systemic lupus erythematosus.Journal of orthopaedic surgery and research · 2022Pooled it
- The Lupus Damage Index Revision Program: Results From the Item Generation and Reduction Phases.Arthritis care & research · 2026Review
- The lupus damage index revision program: Results from the item generation and reduction phases.Lupus science & medicine · 2026Review
- Joint surgery rates in lupus: a long-term cohort study.Lupus science & medicine · 2024Article
- Increased Risk of Common Orthopedic Surgeries for Patients with Rheumatic Diseases in Taiwan.Medicina (Kaunas, Lithuania) · 2022Review
- Increased Incidence of Total Knee Replacement Surgery in Patients With Psoriasis: A Secondary Cohort Analysis of a Nationwide, Population-Based Health Claims Database.Frontiers in medicine · 2021Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundFemale patients with systemic lupus erythematosus (SLE) are prone to have musculoskeletal system involvement, which could lead to joint damage. However, few studies have assessed the incidence of arthroplasty in female patients with SLE. The aim of this study was to investigate the risk of total hip replacement surgery and total knee replacement surgery in patients with SLE.
methodsWe identified 577 female patients with newly diagnosed SLE between 2000 and 2012 using the Taiwan's National Health Insurance Research Database. A comparison cohort was constructed with female patients without SLE in a ratio of 5:1, based on frequency matching for 10-year age interval, and index year, for each patient with SLE. Both cohorts were followed until a diagnosis of the study outcomes or the end of the follow-up period.
resultsFemale patients with SLE showed a significantly higher incidence of receiving total hip replacement surgery (adjusted incidence rate ratio [aIRR] 6.47; P < 0.001), but not total knee replacement surgery (aIRR 1.81; P = 0.227). Moreover, age-group stratified analyses indicated a high incidence for receiving total hip replacement surgery among young female patients with SLE (aIRR 7.70; P = 0.001).
conclusionYoung female patients with SLE had a high risk of receiving total hip replacement surgery, but not total knee replacement surgery.
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Registered trials
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