Evidence map›Paper›PMID 31278791›Full record

ArticleMolecular microbiology2019

A new flavor of entry exclusion in ICE elements provides a selective advantage for the element and its host.

Gary M Dunny, Helmut Hirt

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Gary M DunnyDepartment of Microbiology and Immunology, University of Minnesota, Minneapolis, MN, 55455, USA.ORCID 0000-0002-9436-9006
Helmut HirtDepartment of Microbiology and Immunology, University of Minnesota, Minneapolis, MN, 55455, USA.

Funding

Enterococcal Sex pheromones: impact on antibiotic resistance transfer and ecology of the gastrointestinal tract.R35GM118079 · NIGMS · UNIVERSITY OF MINNESOTA · PI DUNNY, GARY M · 2016 to 2020
$2.1M
NIGMS NIH HHS R35 GM118079
6 · The paper itself

Abstract

Entry exclusion has been described in many bacterial conjugation systems, but their molecular mechanisms are not well understood. In the current issue, Avello et al. describe a new exclusion system in the conjugative element ICEBs1. They identify the yddJ gene as the functional exclusion gene and its target as the protein product of the conG gene. They provide evidence for a possible mechanism and for the contribution of the system to reduce fitness costs of ICE expression.

Indexed as

Bacillus subtilisGene Transfer, HorizontalConjugation, Genetic

Identifiers

PMID31278791
PMCPMC6800755

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.