ReviewSurgery today2020
True esophagogastric junction adenocarcinoma: background of its definition and current surgical trends.
Review in Surgery today, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Comparing Minimally-Invasive and Open Approaches to Siewert II/III Gastro-Esophageal Junction Adenocarcinoma-A Systematic Review and Network Meta-Analysis.World journal of surgery · 2026Pooled it
- Comparison of minimally invasive single-position left transthoracic and esophageal hiatal approach versus laparoscopic transesophageal hiatus approach for Siewert type II adenocarcinoma of the esophagogastric junction.Surgical endoscopy · 2026Article
- Laparoscopic proximal gastrectomy with esophagogastrostomy using overlap method combined with gastric remnant "U"-shaped fold: a retrospective cohort study.Frontiers in surgery · 2026Article
- Clinical application value of modified overlap anastomosis for Siewert type II and III adenocarcinoma of esophagogastric junction.Journal of cancer research and clinical oncology · 2025Article
- Analysis of Risk Factors and Circumferential Distribution of Exposed Cardiac Glands.JGH open : an open access journal of gastroenterology and hepatology · 2025Review
- CT-based radiomics nomogram to predict response of advanced adenocarcinoma of esophagogastric junction to neoadjuvant chemotherapy.Insights into imaging · 2025Article
- Computed tomography-based nomogram of Siewert type II/III adenocarcinoma of esophagogastric junction to predict response to docetaxel, oxaliplatin and S-1.World journal of radiology · 2024Article
- Proposal for T3 classification of esophagogastric junction carcinoma based on the interconnection of extramural anatomical structures.Esophagus : official journal of the Japan Esophageal Society · 2023Review
- Effect of two surgical approaches on the lung function and prognosis of patients with combined esophagogastric cancer.World journal of gastrointestinal surgery · 2023Article
- Utility of robotic surgery for Siewert type II/III adenocarcinoma of esophagogastric junction: transhiatal robotic versus laparoscopic approach.BMC surgery · 2023Article
- Impact of neoadjuvant FLOT treatment of advanced gastric and gastroesophageal junction cancer following surgical therapy.Frontiers in surgery · 2023Article
- Model established based on blood markers predicts overall survival in patients after radical resection of types II and III adenocarcinoma of the esophagogastric junction.World journal of gastrointestinal surgery · 2022Article
- Recent advances in multidisciplinary therapy for adenocarcinoma of the esophagus and esophagogastric junction.World journal of gastroenterology · 2022Review
- Efficacy analysis of Cheng's GIRAFFE reconstruction after proximal gastrectomy for adenocarcinoma of esophagogastric junction.Chinese journal of cancer research = Chung-kuo yen cheng yen chiu · 2022Article
- Evidence-based approach to the treatment of esophagogastric junction tumors.World journal of clinical oncology · 2022Review
- Side-overlap esophagogastric tube (SO-EG) reconstruction after minimally invasive Ivor Lewis esophagectomy or laparoscopic proximal gastrectomy for cancer of the esophagogastric junction.Langenbeck's archives of surgery · 2022Article
- Current treatments and outlook in adenocarcinoma of the esophagogastric junction: a narrative review.Annals of translational medicine · 2022Review
- Accuracy of Preoperative Endoscopy in Determining Tumor Location Required for Surgical Planning for Esophagogastric Junction Cancer.Journal of clinical medicine · 2021Article
- Oncologic Feasibility of Proximal Gastrectomy in Upper Third Advanced Gastric and Esophagogastric Junctional Cancer.Journal of gastric cancer · 2021Article
- Two updates on oesophagogastric junction adenocarcinoma from the fifth WHO classification: Alteration of definition and emphasis on HER2 test.Histology and histopathology · 2021Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
The definition of true esophagogastric junction (EGJ) adenocarcinoma and its surgical treatment are debatable. We review the basis for the current definition and the Japanese surgical strategy in managing true EGJ adenocarcinoma. The Siewert classification is a well-known anatomical classification system for EGJ adenocarcinomas: type II tumors in the region 1 cm above and 2 cm below the EGJ are described as "true carcinoma of the cardia". Coincidentally, this range matches gastric cardiac gland distribution. Conversely, Nishi's classification is generally used to describe EGJ carcinomas, defined as tumors with the center located within 2 cm above and 2 cm below the EGJ, regardless of their histological subtype. This range coincides with the extent of the lower esophageal sphincter combined with gastric cardiac gland distribution. The current Japanese surgical strategy focuses on the tumor range from the EGJ to the esophagus and stomach. According to previous studies, the strategy can be roughly classified into three types. The optimal surgical procedure for true EGJ adenocarcinoma is controversial. However, an ongoing Japanese nationwide prospective trial will help confirm the appropriate standard surgery, including the optimal extent of lymph node dissection.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.