ArticleOsteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA2019
Association between serum uric acid and bone health in adolescents.
Article in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Association between serum vitamin D levels and cardiovascular disease risk in patients with hyperuricemia: A cross-sectional study.PloS one · 2026Article
- Nonlinear Association Between Serum Uric Acid and Femoral Neck Bone Mineral Density in Male Patients with Metabolic Dysfunction-Associated Fatty Liver Disease.Diabetes, metabolic syndrome and obesity : targets and therapy · 2025Article
- Uric Acid Correlates with Serum Levels of Mineral Bone Metabolism and Inflammation Biomarkers in Patients with Stage 3a-5 Chronic Kidney Disease.Medicina (Kaunas, Lithuania) · 2024Article
- BMI mediates the association of serum uric acid with bone health: a cross-sectional study of the National Health and Nutrition Examination Survey (NHANES).BMC musculoskeletal disorders · 2024Article
- Long-Term Differential Effects of Gastric Bypass and Sleeve Gastrectomy on Bone Mineral Density.Journal of the Endocrine Society · 2024Article
- Association between serum uric acid and bone mineral density in males from NHANES 2011-2020.Scientific reports · 2024Article
- Relationship between serum uric acid levels and osteoporosis.Endocrine connections · 2023Review
- A predictive model for hyperuricemia among type 2 diabetes mellitus patients in Urumqi, China.BMC public health · 2023Article
- Association of serum uric acid levels with bone mineral density and the presence of osteoporosis in Chinese patients with Parkinson's disease: a cross-sectional study.Journal of bone and mineral metabolism · 2023Article
- Serum 25-hydroxyvitamin D might be negatively associated with hyperuricemia in U.S. adults: an analysis of the National Health and Nutrition Examination Survey 2007-2014.Journal of endocrinological investigation · 2022Article
- Altered Gut Microbiota in Children With Hyperuricemia.Frontiers in endocrinology · 2022Article
- Serum Uric Acid Level Is Positively Associated With Higher Bone Mineral Density at Multiple Skeletal Sites Among Healthy Qataris.Frontiers in endocrinology · 2021Article
- Age and Gender-Specific Reference Intervals for Uric Acid Level in Children Aged 5-14 Years in Southeast Zhejiang Province of China: Hyperuricemia in Children May Need Redefinition.Frontiers in pediatrics · 2021Article
- Incidence of metabolic syndrome and determinants of its progression in Southern Iran: A 5-year longitudinal follow-up study.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2020Article
- Association of Serum Uric Acid Status With Bone Mineral Density in Adolescents Aged 12-19 Years.Frontiers in medicine · 2020Article
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3 authors.
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Abstract
Previous studies are suggestive of the protective role of uric acid on bone in the middle-aged and elderly. Whether this association exists in younger individuals has not been examined. This investigation showed a significant positive association between serum uric acid and bone parameters among Iranian adolescents.
introductionUric acid (UA) might be linked to bone health, but it is unclear whether its effects on bone are limited to certain population subgroups. This study is aimed at investigating the correlation between serum uric acid levels and bone mineral density (BMD) in Iranian adolescents.
methodsThis cross-sectional study was conducted on 413 (221 girls and 192 boys) Iranian adolescents aged 9-19 years. An analysis of anthropometric, biochemical parameters and bone density was performed on the participants. Measurements included serum uric acid, calcium, phosphorus, alkaline phosphatase, albumin, and vitamin D. They were divided according to their serum UA into the low UA group who had UA ≤ 6 mg/dL and the high UA group with UA > 6 mg/dL. BMD and bone mineral content (BMC) were measured in the total body, lumbar spine, and left femoral neck, using dual energy X-ray absorptiometry (DXA), and bone mineral apparent density (BMAD) was calculated.
resultsA Pearson correlation analysis revealed a significant correlation between UA and bone parameters. In multiple regression analyses adjusted for potential confounders, serum UA was proven to be associated with BMD and BMC at all sites. There was no association between UA, serum calcium, and vitamin D concentrations.
conclusionOur study, as the first research on adolescents, demonstrated a higher bone density in those who had higher UA levels.
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