ArticleScientific reports2019
Adverse perinatal outcomes for obese women are influenced by the presence of comorbid diabetes and hypertensive disorders.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 3 of them syntheses that pooled it.
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Who cites it
22 citing papers in PubMed, 3 syntheses or guidelines pooled it, 33 citations in OpenAlex.
- Global prevalence of multimorbidity during pregnancy: a systematic review and meta-analysis.Reproductive health · 2026Pooled it
- Perinatal and neonatal outcomes among women with multimorbidity during pregnancy globally: a systematic review.BMC pediatrics · 2026Pooled it
- Association between maternal multimorbidity and preterm birth: a systematic review and meta-analysis.BMC pregnancy and childbirth · 2026Pooled it
- Mental health symptoms following a pregnancy complicated by cardiovascular disease: scoping review.BJPsych open · 2026Review
- The Economic Burden of Gestational Diabetes and Body Mass Index Changes Between Pregnancies: A Retrospective Cohort Study.BJOG : an international journal of obstetrics and gynaecology · 2026Article
- Trial design: Evaluating the safety, feasibility, and acceptability of time-restricted eating in pregnant women with obesity.Contemporary clinical trials · 2026Article
- Food, Built and Socio-Economic Environments and Maternal-Infant Outcomes: A Geospatial and Structural Equation Modelling of 163 000 Births.BJOG : an international journal of obstetrics and gynaecology · 2026Article
- Evaluating childbirth options for women with obesity: a multi-criteria decision analysis.Frontiers in global women's health · 2026Article
- The relationship between the Charlson Comorbidity Index and anorexia in older adults: the mediating role of depressive symptoms.Frontiers in nutrition · 2026Article
- Experiencing weight stigma during childbirth increases the odds of cesarean birth.BMC pregnancy and childbirth · 2025Article
- Crosstalk between hypertension and diabetes: focusing on pregnancy and offspring. A systematic review.Frontiers in physiology · 2025Review
- Maternal Obesity and Differences in Child Urine Metabolome.Metabolites · 2024Article
- Targeting the incretin system in obesity and type 2 diabetes mellitus.Nature reviews. Endocrinology · 2024Review
- Neonatal upper limb fractures - a narrative overview of the literature.BMC pediatrics · 2024Article
- Prepregnancy body mass index and adverse perinatal outcomes in the presence of other maternal risk factors.AJOG global reports · 2023Article
- Association Between Social Determinants of Health Issues and Maternal Obesity Among American Racial/Ethnic Groups.International journal of MCH and AIDS · 2023Article
- The Epidemiology and Mechanisms of Lifetime Cardiopulmonary Morbidities Associated With Pre-Pregnancy Obesity and Excessive Gestational Weight Gain.Frontiers in cardiovascular medicine · 2022Review
- Obesity Class Impacts Adverse Maternal and Neonatal Outcomes Independent of Diabetes.Frontiers in endocrinology · 2022Article
- Explaining the Black-White Disparity in Preterm Birth: A Consensus Statement From a Multi-Disciplinary Scientific Work Group Convened by the March of Dimes.Frontiers in reproductive health · 2021Review
- Country-Level Analysis of the Association between Maternal Obesity and Neonatal Mortality in 34 Sub-Saharan African Countries.Annals of global health · 2019Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Maternal obesity often occurs together with comorbid diabetes and hypertensive disorders. All three conditions are independently associated with negative perinatal outcomes. Our objective was to determine the risk and burden of adverse perinatal outcome that could be attributed to maternal obesity in combination with a comorbid status. We analyzed data from 324'664 singleton deliveries in Switzerland between 2005 and 2016. For the association of maternal obesity in the presence or absence of comorbidities with various perinatal outcomes, we estimated adjusted relative risk (RR) using multivariable regression modeling and determined the multivariable-adjusted attributable fraction of the population (AFp). Obesity was a main predictor for macrosomia, fracture of the clavicle, failure to progress in labor and prolonged labor. By stratifying women based on comorbidities, we identified significantly increased risk for preterm birth and early neonatal death only for women diagnosed with a comorbidity. However, various other outcomes were independently associated with either obesity or comorbidities. The AFp showed greatest reduction in comorbidities (15.4/15.0/13.2%), in macrosomia (6.3%) and in shoulder dystocia (4.8%) if all women were to become non-obese. We suggest that comorbidities such as diabetes and hypertensive disorders should be considered when relating maternal obesity to adverse perinatal outcomes.
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