Evidence map›Paper›PMID 31278297›Full record

ArticleScientific reports2019

EIT monitors valid and robust regional ventilation distribution in pathologic ventilation states in porcine study using differential DualEnergy-CT (ΔDECT).

Sebastian D Reinartz, Michael Imhoff, René Tolba, Felix Fischer, Eike G Fischer, Eckhard Teschner, Sabine Koch, Yvo Gärber, Peter Isfort, Felix Gremse

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

  1. Trial
  2. Article
  3. Observational
  4. Article
  5. Observational
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Sebastian D ReinartzDepartment of Diagnostic and Interventional Radiology, University Hospital, RWTH Aachen University, 52074, Aachen, Germany. sreinartz@ukaachen.de.ORCID http://orcid.org/0000-0003-1769-4953
Michael ImhoffDepartment for Medical Informatics, Biometry and Epidemiology, Ruhr University of Bochum, 44780, Bochum, Germany.
René TolbaInstitute of Laboratory Animal Science, University Hospital, RWTH Aachen University, 52074, Aachen, Germany.
Felix FischerDrägerwerk AG & Co. KGaA, Moislinger Allee 53-55, 23558, Lübeck, Germany.
Eike G FischerAix Scientifics CRO, Theaterstr. 7, 52062, Aachen, Germany.
Eckhard TeschnerDrägerwerk AG & Co. KGaA, Moislinger Allee 53-55, 23558, Lübeck, Germany.
Sabine KochInstitute of Laboratory Animal Science, University Hospital, RWTH Aachen University, 52074, Aachen, Germany.
Yvo GärberDrägerwerk AG & Co. KGaA, Moislinger Allee 53-55, 23558, Lübeck, Germany.
Peter IsfortDepartment of Diagnostic and Interventional Radiology, University Hospital, RWTH Aachen University, 52074, Aachen, Germany.
Felix GremseInstitute for Experimental Molecular Imaging, University Hospital, RWTH Aachen University, 52074, Aachen, Germany.
RWTH Aachen University · DEDräger (Germany) · DEAixtron (Germany) · DERuhr University Bochum · DEUniversitätsklinikum Aachen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

It is crucial to precisely monitor ventilation and correctly diagnose ventilation-related pathological states for averting lung collapse and lung failure in Intensive Care Unit (ICU) patients. Although Electrical Impedance Tomography (EIT) may deliver this information continuously and non-invasively at bedside, to date there are no studies that systematically compare EIT and Dual Energy CT (DECT) during inspiration and expiration (ΔDECT) regarding varying physiological and ICU-typical pathological conditions such as atelectasis. This study aims to prove the accuracy of EIT through quantitative identification and monitoring of pathological ventilation conditions on a four-quadrant basis using ΔDECT. In a cohort of 13 pigs, this study investigated systematic changes in tidal volume (TV) and positive end-expiratory pressure (PEEP) under physiological ventilation conditions. Pathological ventilation conditions were established experimentally by single-lung ventilation and pulmonary saline lavage. Spirometric data were compared to voxel-based entire lung ΔDECT, and EIT intensities were compared to ΔDECT of a 12-cm slab of the lung around the EIT belt, the so called ΔDECT

Indexed as

Pulmonary VentilationRespiratory Function TestsTomographyTomography, X-Ray ComputedAnimalsData AnalysisElectric ImpedanceImage Processing, Computer-AssistedMonitoring, PhysiologicSwine

Identifiers

PMID31278297
PMCPMC6611907
OpenAlexW2955486757

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.