ArticleProceedings of the National Academy of Sciences of the United States of America1988
Localization of the human JUN protooncogene to chromosome region 1p31-32.
Article in Proceedings of the National Academy of Sciences of the United States of America, 1988. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
22 citing papers in PubMed, 61 citations in OpenAlex.
- Targeted transcriptomic analysis of well-differentiated and dedifferentiated liposarcoma reveals multiple dysregulated pathways including glucose metabolism, TGF-β, and HIF-1 signaling.Frontiers in oncology · 2024Article
- Structural and Functional Properties of Activator Protein-1 in Cancer and Inflammation.Evidence-based complementary and alternative medicine : eCAM · 2022Review
- Liposarcoma: molecular targets and therapeutic implications.Cellular and molecular life sciences : CMLS · 2016Review
- Concurrent MCL1 and JUN amplification in pseudomyxoma peritonei: a comprehensive genetic profiling and survival analysis.Journal of human genetics · 2014Article
- Association of c-Jun gene polymorphism with susceptibility to systemic lupus erythematosus in a Chinese population.DNA and cell biology · 2012Article
- c-Jun, at the crossroad of the signaling network.Protein & cell · 2011Review
- Jun, the oncoprotein.Oncogene · 2001Review
- Regional localization of the rat genes encoding the cAMP-specific phosphodiesterases 3 (Pde4d) and 4 (Pde4b) and the tyrosinase-related protein 1 (Tyrp1).Mammalian genome : official journal of the International Mammalian Genome Society · 1996Article
- Involvement of the ALL-1 gene in a solid tumor.Proceedings of the National Academy of Sciences of the United States of America · 1995Article
- Assignment of rat Jun family genes to chromosome 19 (Junb), chromosome 5q31-33 (Jun), and chromosome 16 (Jund).Mammalian genome : official journal of the International Mammalian Genome Society · 1994Article
- A genetic linkage map of rat chromosome 5 reveals extensive linkage conservation with mouse chromosome 4.Mammalian genome : official journal of the International Mammalian Genome Society · 1994Article
- Enhanced tumorigenicity of an Epstein-Barr virus-transformed lymphoblastoid cell line is associated with a unique 1:18 chromosomal translocation and decreased expression of lymphocyte function associated antigen-1a (CD11A).The American journal of pathology · 1993Article
- Retroposition in a family of carcinoma-associated antigen genes.Molecular and cellular biology · 1993Article
- A novel endothelial cell surface receptor tyrosine kinase with extracellular epidermal growth factor homology domains.Molecular and cellular biology · 1992Article
- Complex intrachromosomal rearrangement in the process of amplification of the L-myc gene in small-cell lung cancer.Molecular and cellular biology · 1992Article
- Comparative map for mice and humans.Mammalian genome : official journal of the International Mammalian Genome Society · 1992Review
- Chromosome assignment of four RAS-related RAB genes.Human genetics · 1991Article
- Comparative map for mice and humans.Mammalian genome : official journal of the International Mammalian Genome Society · 1991Review
- Molecular mapping of the mouse db mutation.Proceedings of the National Academy of Sciences of the United States of America · 1990Article
- The human homolog of the myeloproliferative virus maps to chromosome band 1p34.Human genetics · 1989Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
The oncogene jun is the putative transforming gene of avian sarcoma virus 17; jun appears to be derived from a gene of the chicken genome and has homologues in several other vertebrate species. Recent genetic and immunological data indicate that jun codes for a protein that is closely related and probably identical to the transcription factor AP-1. We have isolated a genomic DNA clone encompassing the human cellular counterpart of the gene, JUN, and used this DNA to determine the chromosomal location of the gene. A panel of DNA preparations derived from rodent-human somatic cell hybrids with defined chromosome complements was first screened with the JUN probe. This Southern blot analysis indicated that JUN is situated on the short arm of chromosome 1. In situ hybridization then assigned JUN to chromosome region 1p31-32, a chromosomal region involved in both translocations and deletions of chromosomes seen in human malignancies.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.