ArticleBMJ open2019
Helping people discontinue long-term antidepressants: views of health professionals in UK primary care.
Article in BMJ open, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 32 citations in OpenAlex.
- Discontinuing antidepressant medication: a qualitative evidence synthesis and logic model based on health professionals' views.BMC health services research · 2025Pooled it
- An assessment of the reporting of tapering methods in antidepressant discontinuation trials using the TIDieR checklist.International journal of clinical pharmacy · 2023Pooled it
- Structured Online Support to Inform and Assist Antidepressant Deprescribing in Primary Care (WiserAD Tool): Protocol for a Pragmatic Randomized Controlled Trial.JMIR research protocols · 2026Article
- Combined nicotinamide riboside and magnesium-l-theanine protects against chronic stress-induced gut-liver injury by modulating NAD⁺ and metabolic pathways.Molecular biology reports · 2025Article
- 'I Wish It Were More Often Told to People Before They Are Prescribed These Medications How Hard It Is to Get Off Them': A Qualitative Descriptive Analysis of Free-Text Responses to a Survey on Reducing and Stopping Psychiatric Medication.Health expectations : an international journal of public participation in health care and health policy · 2025Article
- Translational framework for implementation evaluation and research: implementation strategies derived from normalization process theory.Implementation science : IS · 2025Article
- Healthcare Providers' Perspectives on Antidepressant Discontinuation: A Focus Group Study.Basic & clinical pharmacology & toxicology · 2025Article
- The missing link? Pharmacists' perspectives on discontinuation of long-term antidepressants: a qualitative study.Therapeutic advances in psychopharmacology · 2025Article
- Article
- [Prescription of antidepressants in primary care: a descriptive study on medical professionals' confidence].Cadernos de saude publica · 2024Article
- The brain-gut-microbiota axis in the treatment of neurologic and psychiatric disorders.Arquivos de neuro-psiquiatria · 2023Review
- Self-reported reasons for reducing or stopping antidepressant medications in primary care: thematic analysis of thePrimary health care research & development · 2023Article
- Antidepressant medication prescribing patterns in Irish general practice from 2016 to 2020 to assess for long-term use.Irish journal of medical science · 2022Article
- 'Never change a winning team': GPs' perspectives on discontinuation of long-term antidepressants.Scandinavian journal of primary health care · 2021Article
- A Digital Intervention for Primary Care Practitioners to Support Antidepressant Discontinuation (Advisor for Health Professionals): Development Study.Journal of medical Internet research · 2021Article
- Exploration of GP perspectives on deprescribing antidepressants: a qualitative study.BMJ open · 2021Article
- Article
- General practitioners' and psychiatrists' attitudes towards antidepressant withdrawal.BJPsych open · 2020Article
- Barriers to discontinuing antidepressants in patients with depressive and anxiety disorders: a review of the literature and clinical recommendations.Therapeutic advances in psychopharmacology · 2020Review
- The 'patient voice': patients who experience antidepressant withdrawal symptoms are often dismissed, or misdiagnosed with relapse, or a new medical condition.Therapeutic advances in psychopharmacology · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 2 institutions in 1 country.
Funding
Abstract
objectiveThe aims of this paper were to identify, characterise and explain clinician factors that shape decision-making around antidepressant discontinuation in UK primary care.
designFour focus groups and three interviews were conducted and analysed using thematic analysis.
participantsTwenty-one general practitioners (GPs), four GP assistants, seven nurses and six community mental health team workers and psychotherapists took part in focus groups and interviews.
settingParticipants were recruited from seven primary care regions and two National Health Service Trusts providing community mental health services in the South of England.
resultsParticipants highlighted a number of barriers and enablers to discussing discontinuation with patients. They held a range of views around responsibility, with some suggesting it was the responsibility of the health professional (HP) to broach the subject, and others suggesting responsibility rested with the patients. HPs were concerned about destabilising the current situation, discussed how continuity and knowing the patient facilitated discontinuation talks, and discussed how confidence in their professional skills and knowledge affected whether they elected to raise discontinuation in consultations.
conclusionsFindings indicate a need to consider support for HPs in the management of antidepressant medication and discussions of discontinuation in particular. They may also benefit from support around their fears of patient relapse and awareness of when and how to initiate discussions about discontinuation with their patients.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.