Evidence map›Paper›PMID 31277907›Full record

ArticleJournal of Ayurveda and integrative medicine

Hepatoprotective effect of Lobelia alsinoides Lam. in Wistar rats.

Raj R V Binitha, M A Shajahan, Jaseer Muhamed, Thapasimuthu V Anilkumar, S Premlal, V C Indulekha

Open access · goldAbstract read
In one paragraph

Article in Journal of Ayurveda and integrative medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
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  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Raj R V BinithaDrug Standardisation Unit, Govt. Ayurveda College, Thiruvananthapuram, Kerala, India. Electronic address: drbinithasreejith@gmail.com.
M A ShajahanDept. of Dravyagunavijnanam, Govt. Ayurveda College, Thiruvananthapuram, Kerala, India.
Jaseer MuhamedRegional Occupational Health Centre (Southern), ICMR Complex, Kannamangala PO, Poojanahalli Road, Devanahalli Thaluk, Bangaluru 562110, Karnataka, India.
Thapasimuthu V AnilkumarDivision of Experimental Pathology, Biomedical Technology Wing, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Thiruvananthapuram 695012, India.
S PremlalDrug Standardisation Unit, Govt. Ayurveda College, Thiruvananthapuram, Kerala, India.
V C IndulekhaDept. of Dravyagunavijnanam, Govt. Ayurveda College, Thiruvananthapuram, Kerala, India.
Vaidyaratnam P.S. Varier Ayurveda College · INSree Chitra Thirunal Institute for Medical Sciences and Technology · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTraditional healing practitioners of South India use fine paste (an Ayurvedic dosage form known as 'kalka') of Lobelia alsinoides Lam., an ethno medicinal plant for curing hepatic diseases.

objectiveTo evaluate in-vivo hepatoprotective effect of a candidate formulation viz. kalka containing whole plant (L. alsinoides Lam.) in rat model of Carbon-tetrachloride (CCl MATERIALS &

methodsHepatotoxicity was induced in Wistar albino rats by oral administration of 1.25 ml/kg CCl

resultsThe animals treated with the fine paste of L. alsinoides did not show an elevation in the biochemical values compared to CCl

conclusionsFrom the study, it was obvious that L. alsinoides had significant hepatoprotective effect in CCl

Indexed as

AyurvedakalkaLobelia alsinoides Lam.

Identifiers

PMID31277907
PMCPMC7772512
OpenAlexW2955685652

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.