Evidence map›Paper›PMID 31277791›Full record

ArticleThe American journal of cardiology2019

The Evolving Management of Aortic Valve Disease: 5-Year Trends in SAVR, TAVR, and Medical Therapy.

Andrew M Goldsweig, Hyo Jung Tak, Li-Wu Chen, Herbert D Aronow, Binita Shah, Dhaval S Kolte, Poonam Velagapudi, Nihar Desai, Molly Szerlip, J Dawn Abbott

Open access · greenAbstract readComparative Study
In one paragraph

Article in The American journal of cardiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
5.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 52 citations in OpenAlex.

  1. Article
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  8. Breaking Down Barriers to Transcatheter Aortic Valve Replacement.Journal of the Society for Cardiovascular Angiography & Interventions · 2024
    Article
  9. Aortic Stenosis Risk in Rheumatoid Arthritis.JAMA internal medicine · 2023
    Article
  10. Article
  11. Article
  12. Trends in Medicare Payments for Beneficiaries With Aortic Stenosis.Journal of the American Heart Association · 2022
    Article
  13. Utilization and outcomes of aortic valve replacements (from the United States readmissions database).American heart journal plus : cardiology research and practice · 2022
    Article
  14. A novel endovascular treatment for transcatheter aortic valve embolization.Journal of vascular surgery cases and innovative techniques · 2021
    Article
  15. Article
  16. Supraglottic Airway Use for Transfemoral-Transcatheter Aortic Valve Replacement.Journal of cardiothoracic and vascular anesthesia · 2020
    Article
  17. Article
  18. Review
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 7 institutions in 1 country.

Andrew M GoldsweigDivision of Cardiovascular Medicine, University of Nebraska Medical Center, Omaha, Nebraska. Electronic address: andrew.goldsweig@unmc.edu.
Hyo Jung TakDepartment of Health Services Research and Administration, University of Nebraska Medical Center, Omaha, Nebraska.
Li-Wu ChenDepartment of Health Services Research and Administration, University of Nebraska Medical Center, Omaha, Nebraska.
Herbert D AronowDivision of Cardiovascular Medicine, Brown University and Lifespan Cardiovascular Institute, Providence, Rhode Island.
Binita ShahDivision of Cardiology, VA New York Harbor Healthcare and New York University School of Medicine, New York, New York.
Dhaval S KolteDivision of Cardiovascular Medicine, Harvard University and Massachusetts General Hospital, Boston, Massachusetts.
Poonam VelagapudiDivision of Cardiovascular Medicine, University of Nebraska Medical Center, Omaha, Nebraska.
Nihar DesaiDivision of Cardiovascular Medicine, Yale University and Yale New Haven Hospital, New Haven, Connecticut.
Molly SzerlipDepartment of Interventional Cardiology, The Heart Hospital, Baylor Plano, Plano, Texas.
J Dawn AbbottDivision of Cardiovascular Medicine, Brown University and Lifespan Cardiovascular Institute, Providence, Rhode Island.
University of Nebraska Medical Center · USBrown University · USHarvard University · USHeart Hospital Baylor Plano · USNebraska Medical Center · USVA NY Harbor Healthcare System · USYale New Haven Hospital · US

Funding

Anti-inflammatory therapy during percutaneous coronary interventionIK2CX001074 · VA · VA MEDICAL CENTER · PI SHAH, BINITA · 2016 to 2021
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CSRD VA IK2 CX001074
6 · The paper itself

Abstract

Aortic stenosis (AS) and regurgitation (AR) may be treated with surgical aortic valve replacement (SAVR), transcatheter AVR (TAVR), or medical therapy (MT). Data are lacking regarding the usage of SAVR, TAVR, and MT for patients hospitalized with aortic valve disease and the characteristics of the patients and hospitals associated with each therapy. From the Nationwide Readmissions Database, we determined utilization trends for SAVR, TAVR, and MT in patients with aortic valve disease admitted from 2012 to 2016 for valve replacement, heart failure, unstable angina, non-ST-elevation myocardial infarction, or syncope. We also performed multinomial logistic regressions to investigate associations between patient and hospital characteristics and treatment. Among 366,909 patients hospitalized for aortic valve disease, there was a 48.1% annual increase from 2012 through 2016. Overall, 19.9%, 6.7%, and 73.4% of patients received SAVR, TAVR, and MT, respectively. SAVR decreased from 21.9% in 2012 to 18.5% in 2016, whereas TAVR increased from 2.6% to 12.5%, and MT decreased from 75.5% to 69.0%. Older age, female sex, greater severity of illness, more admission diagnoses, not-for-profit hospitals, large hospitals, and urban teaching hospitals were associated with greater use of TAVR. In multivariable analysis, likelihood of TAVR relative to SAVR increased 4.57-fold (95% confidence interval 4.21 to 4.97). TAVR has increased at the expense of both SAVR and MT, a novel finding. However, this increase in TAVR was distributed inequitably, with certain patients more likely to receive TAVR certain hospitals more likely to provide TAVR. With the expected expansion of indications, inequitable access to TAVR must be addressed.

Indexed as

AgedAged, 80 and overAortic Valve InsufficiencyAortic Valve StenosisCohort StudiesConservative TreatmentDatabases, FactualEchocardiographyFemaleHeart Valve Prosthesis ImplantationHospital MortalityHumansLogistic ModelsMaleMiddle AgedMultivariate Analysis

Identifiers

PMID31277791
PMCPMC6880229
OpenAlexW2955739149

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.