Trial reportBMC geriatrics2019
Factors related to health-related quality of life in older people with multimorbidity and high health care consumption over a two-year period.
Trial report in BMC geriatrics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01446757 (Effectiveness of a Comprehensive CGA on Frailty in Community-dwelling Elderly People - A Randomised, Controlled Trial), which is not on this map. Cited by 53 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effectiveness of a Comprehensive CGA on Frailty in Community-dwelling Elderly People - A Randomised, Controlled Trial
Who cites it
53 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Home-Based Comprehensive Geriatric Assessment for Community-Dwelling, At-Risk, Frail Older Adults: A Systematic Review and Meta-Analysis.Journal of the American Geriatrics Society · 2025Pooled it
- Pooled it
- The impact of stroke on the ability to live an independent life at old age: a community-based cohort study of Swedish men.BMC geriatrics · 2023Pooled it
- Pooled it
- Machine-Learning Prediction of Health-Related Quality of Life Among Community-Dwelling Middle-Aged and Older Adults Living Alone: A Secondary Analysis of the 2022 Korea Health Panel.Healthcare (Basel, Switzerland) · 2026Article
- Associations between Fear of Crime and Symptom Burden among Non-victimized Older Adults: Findings from the Swedish Population-Based Study "Good Aging in Skåne".Annals of geriatric medicine and research · 2026Article
- Long-term changes in health-related quality of life among Australian adults with psychological distress: a 16-year perspective.Archives of public health = Archives belges de sante publique · 2025Article
- Development and psychometric testing of symptom severity scale in older patients with cardiometabolic multimorbidity.BMC geriatrics · 2025Article
- Navigating fragmented care: a qualitative study on multimorbidity management challenges in Beijing's tiered healthcare system.BMC primary care · 2025Article
- Exploring Perceived Limitations to Daily Activities Due to Chronic Conditions: A Person-Centered Approach to Measuring Multimorbidity Severity.The journals of gerontology. Series A, Biological sciences and medical sciences · 2024Article
- Supportive and palliative care needs among older adults in India: an estimation using a nationally representative survey.BMC palliative care · 2024Article
- Adapted Taekwondo Improves Postural Balance and Health-Related Quality of Life Concerning Multicomponent Training and Walking Exercise in Older Females: A Randomized Controlled Trial (TKD and Aging Project).Journal of clinical medicine · 2024Article
- The relationship between childhood hunger experiences and activities of daily living disability: a mediating role of depression.BMC public health · 2024Article
- Comparison of quality of life of older adults living in foster families versus nursing homes. Results from the KASA studies.The journal of nutrition, health & aging · 2024Article
- A Review of Risk Factors for Polypharmacy: Age, Level of Education, and Physician's Attitude.Cureus · 2024Review
- Association of a healthy ageing index with health-related outcomes in a multi-ethnic cohort from Singapore.BMC geriatrics · 2024Article
- Thanks for hearing me: key elements of primary care according to older patients.Scandinavian journal of primary health care · 2024Article
- Living with multimorbidity: A qualitative exploration of shared experiences of patients, family caregivers, and healthcare professionals in managing symptoms in the United States.Journal of advanced nursing · 2024Article
- Changes over time in patient-reported outcomes in patients with heart failure.ESC heart failure · 2024Article
- Quantitative relationship between grip strength and quality of life in the older adult based on a restricted cubic spline model.Frontiers in public health · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe prevalence of multimorbidity is increasing worldwide, and older people with multimorbidity are frequent users of health care services. Since multimorbidity has a significant negative impact on Health-related Quality of Life (HrQoL) and is more common in older age it would be expected that factors related to HrQoL in this group might have been thoroughly researched, but this is not the case. Furthermore, it is important to look at old people living at home, considering the shift from residential to home-based care. Therefore, we aim to investigate factors that are related to HrQoL in older people with multimorbidity and high health care consumption, living at home.
methodsThis is a secondary analysis of a RCT study conducted in a municipality in south-eastern Sweden. The study had a longitudinal design with a two-year follow-up period assessing HrQoL, symptom burden, activities of daily living, physical activity and depression.
resultsIn total, 238 older people with multimorbidity and high health care consumption, living at home were included (mean age 82, 52% female). A multiple linear regression model including symptom burden, activities of daily living and depression as independent variables explained 64% of the HrQoL. Higher symptom burden, lower ability in activities of daily living and a higher degree of depression were negatively related to HrQoL. Depression at baseline and a change in symptom burden over a two-year period explained 28% of the change in HrQoL over a two-year period variability. A higher degree of depression at baseline and negative change in higher symptom burden were related to a decrease in HrQoL over a two-year period.
conclusionIn order to facilitate better delivery of appropriate health care to older people with high health care consumption living at home it is important to assess HrQoL, and HrQoL over time. Symptom burden, activities of daily living, depression and change in symptom burden over time are important indicators for HrQoL.
trial registrationClinicaltrials.gov identifier: NCT01446757 , the trial was registered prospectively with the date of trial registration October 5
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.