ArticleMicrobial cell factories2019
Inducing perylenequinone production from a bambusicolous fungus Shiraia sp. S9 through co-culture with a fruiting body-associated bacterium Pseudomonas fulva SB1.
Article in Microbial cell factories, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed, 52 citations in OpenAlex.
- Spermidine stimulates hypocrellin A biosynthesis through nitric oxide signaling in Shiraia sp. S9.Bioresources and bioprocessing · 2026Article
- Fungal-fungal interaction between Sanghuangporus vaninii and its endophytic Fusarium solani rewires host secondary metabolism to boost bioactive metabolite production.Microbial cell factories · 2026Article
- Interplay betweenMycology · 2026Article
- Dereplication-Guided Isolation of 3‑ACS omega · 2025Article
- Scaling up the production of fungal perylenequinones and investigating their biosynthesis through stable isotope labeling.Microbial cell factories · 2025Article
- Fruiting body-associated Pseudomonas contact triggers ROS-mediated perylenequinone biosynthesis in Shiraia mycelium culture.Bioresources and bioprocessing · 2025Article
- Induced effect of NaWorld journal of microbiology & biotechnology · 2025Article
- Production of fungal hypocrellin photosensitizers: Exploiting bambusicolous fungi and elicitation strategies in mycelium cultures.Mycology · 2025Review
- Energy Metabolism Enhance Perylenequinone Biosynthesis inInternational journal of molecular sciences · 2024Article
- Bamboo polysaccharides elicit hypocrellin A biosynthesis of a bambusicolous fungus Shiraia sp. S9.World journal of microbiology & biotechnology · 2023Article
- Volatiles ofSynthetic and systems biotechnology · 2023Article
- Community composition and trophic mode diversity of fungi associated with fruiting body of medicinal Sanghuangporus vaninii.BMC microbiology · 2022Article
- Contrasting regulation of live Bacillus cereus No.1 and its volatiles on Shiraia perylenequinone production.Microbial cell factories · 2022Article
- Identification and profiling of the community structure and potential function of bacteria from the fruiting bodies of Sanghuangporus vaninii.Archives of microbiology · 2022Article
- CRISPR/Cas9-Mediated Genome Editing forInternational journal of molecular sciences · 2022Article
- Review
- L-Arginine enhanced perylenequinone production in the endophytic fungus Shiraia sp. Slf14(w) via NO signaling pathway.Applied microbiology and biotechnology · 2022Article
- Fungal perylenequinones.Mycological progress · 2022Review
- The signaling role of extracellular ATP in co-culture of Shiraia sp. S9 and Pseudomonas fulva SB1 for enhancing hypocrellin A production.Microbial cell factories · 2021Article
- Phylogenetic Position ofJournal of fungi (Basel, Switzerland) · 2021Article
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Authors and funding
3 authors at 1 institution in 1 country.
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Abstract
backgroundFungal perylenequinonoid (PQ) pigments from Shiraia fruiting body have been well known as excellent photosensitizers for medical and agricultural uses. The fruiting bodies are colonized by a diverse bacterial community of unknown function. We screened the companion bacteria from the fruiting body of Shiraia sp. S9 and explored the bacterial elicitation on fungal PQ production.
resultsA bacterium Pseudomonas fulva SB1 isolated from the fruiting body was found to stimulate the production of fungal PQs including hypocrellins A, C (HA and HC), and elsinochromes A-C (EA, EB and EC). After 2 days of co-cultures, Shiraia mycelium cultures presented the highest production of HA (325.87 mg/L), about 3.20-fold of that in axenic culture. The co-culture resulted in the induction of fungal conidiation and the formation of more compact fungal pellets. Furthermore, the bacterial treatment up-regulated the expression of polyketide synthase gene (PKS), and activated transporter genes of ATP-binding cassette (ABC) and major facilitator superfamily transporter (MFS) for PQ exudation.
conclusionsWe have established a bacterial co-culture with a host Shiraia fungus to induce PQ biosynthesis. Our results provide a basis for understanding bacterial-fungal interaction in fruiting bodies and a practical co-culture process to enhance PQ production for photodynamic therapy medicine.
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