Evidence map›Paper›PMID 31277620›Full record

ArticleBMC psychiatry2019

Cocaine use disorder in females is associated with altered social decision-making: a study with the prisoner's dilemma and the ultimatum game.

Thiago Wendt Viola, João Paulo Otolia Niederauer, Bruno Kluwe-Schiavon, Breno Sanvicente-Vieira, Rodrigo Grassi-Oliveira

Open access · goldAbstract read
In one paragraph

Article in BMC psychiatry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Thiago Wendt ViolaPontifical Catholic University of Rio Grande do Sul (PUCRS), Developmental Cognitive Neuroscience Lab, Avenida Ipiranga 6690 - Prédio 63, Jardim Botânico, Porto Alegre, RS, Brazil.
João Paulo Otolia NiederauerPontifical Catholic University of Rio Grande do Sul (PUCRS), Developmental Cognitive Neuroscience Lab, Avenida Ipiranga 6690 - Prédio 63, Jardim Botânico, Porto Alegre, RS, Brazil.
Bruno Kluwe-SchiavonExperimental and Clinical Pharmacopsychology Laboratory Department of Psychiatry Psychotherapy and Psychosomatics Psychiatric Hospital, University of Zurich, Zürich, Switzerland.
Breno Sanvicente-VieiraPontifical Catholic University of Rio Grande do Sul (PUCRS), Developmental Cognitive Neuroscience Lab, Avenida Ipiranga 6690 - Prédio 63, Jardim Botânico, Porto Alegre, RS, Brazil.
Rodrigo Grassi-OliveiraPontifical Catholic University of Rio Grande do Sul (PUCRS), Developmental Cognitive Neuroscience Lab, Avenida Ipiranga 6690 - Prédio 63, Jardim Botânico, Porto Alegre, RS, Brazil. rodrigo.grassi@pucrs.br.ORCID 0000-0001-9911-5921
Pontifícia Universidade Católica do Rio Grande do Sul · BRUniversity of Zurich · CH

Funding

Gene-environment interactions in COCCaINE Use Disorder: Collaborative Case-Control Initiative in Coccaine AddictionR01DA044859 · NIDA · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI GRASSI-OLIVEIRA, RODRIGO, SCHMITZ, JOY MARIE · 2017 to 2021
$2.8M
NIDA NIH HHS R01 DA044859
6 · The paper itself

Abstract

backgroundChronic cocaine use is associated with cognitive deficits, including poor performance on neuropsychological tasks of memory, executive functions, theory of mind and decision-making. However, the relationship between cocaine use disorder and social decision-making remains unclear. This is particularly relevant given the fact that many cocaine abusers present impairments in social functioning. In this sense, game theory paradigms have been helping to comprehend the behavior of psychiatric patients when they directly engage in social situations, which may better approximate many of their real-life choices.

methodsThe present study investigated social decision-making in individuals with or without cocaine use disorder, examining their behavior in the Prisoner's Dilemma and in the Ultimatum Game. Thus, 129 females diagnosed with cocaine use disorder and 55 females with no history of substance abuse were recruited and performed both social decision-making tasks. Additional assessments included information about demographics, patterns of substance consumption and executive function performance.

resultsFemales with cocaine use disorder opted more often to not defect in the Prisoner's Dilemma, while in the Ultimatum Game they frequently chose to accept the first and unfair offer as responders. These effects were more pronounced within females with long-term history of cocaine use. Associations between cocaine use disorder and altered social decision-making were independent from demographic and executive function variables.

conclusionsThe influence of cocaine use disorder on social decision-making was detected in both game paradigms, resulting in more cooperative behavior in the Prisoner's Dilemma and higher acceptance rate of unfair offers in the Ultimatum Game. Further studies should focus on investigating these associations to shed light on the putative biopsychosocial factors underlying the observed effects.

Indexed as

Decision MakingPrisoner DilemmaSocial BehaviorAdultChoice BehaviorCocaine-Related DisordersCooperative BehaviorFemaleGames, RecreationalHumansCocaineCocaine-related disordersCognitionDecision making

Identifiers

PMID31277620
PMCPMC6612218
OpenAlexW2955788331

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.