Evidence map›Paper›PMID 31277465›Full record

ArticleInternational journal of molecular sciences2019

EDB-FN Targeted Peptide-Drug Conjugates for Use against Prostate Cancer.

Shang Eun Park, Kiumars Shamloo, Timothy A Kristedja, Shaban Darwish, Marco Bisoffi, Keykavous Parang, Rakesh Kumar Tiwari

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. Review
  3. Research advances in peptide‒drug conjugates.Acta pharmaceutica Sinica. B · 2023
    Review
  4. Article
  5. Peptides for Health Benefits 2019.International journal of molecular sciences · 2020
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Shang Eun ParkCenter for Targeted Drug Delivery, Department of Biomedical and Pharmaceutical Sciences, Chapman University School of Pharmacy, Harry and Diane Rinker Health Science Campus, 9401 Jeronimo Road, Irvine, CA 92618, USA.
Kiumars ShamlooCenter for Targeted Drug Delivery, Department of Biomedical and Pharmaceutical Sciences, Chapman University School of Pharmacy, Harry and Diane Rinker Health Science Campus, 9401 Jeronimo Road, Irvine, CA 92618, USA.
Timothy A KristedjaBiochemistry and Molecular Biology, Schmid College of Science and Technology, Chapman University, Orange, CA 92866, USA.
Shaban DarwishCenter for Targeted Drug Delivery, Department of Biomedical and Pharmaceutical Sciences, Chapman University School of Pharmacy, Harry and Diane Rinker Health Science Campus, 9401 Jeronimo Road, Irvine, CA 92618, USA.
Marco BisoffiCenter for Targeted Drug Delivery, Department of Biomedical and Pharmaceutical Sciences, Chapman University School of Pharmacy, Harry and Diane Rinker Health Science Campus, 9401 Jeronimo Road, Irvine, CA 92618, USA.
Keykavous ParangCenter for Targeted Drug Delivery, Department of Biomedical and Pharmaceutical Sciences, Chapman University School of Pharmacy, Harry and Diane Rinker Health Science Campus, 9401 Jeronimo Road, Irvine, CA 92618, USA.ORCID 0000-0001-8600-0893
Rakesh Kumar TiwariCenter for Targeted Drug Delivery, Department of Biomedical and Pharmaceutical Sciences, Chapman University School of Pharmacy, Harry and Diane Rinker Health Science Campus, 9401 Jeronimo Road, Irvine, CA 92618, USA. tiwari@chapman.edu.ORCID 0000-0003-3701-4548
Target (United States) · USChapman University · US

Funding

Chapman University FRDC and Graduate Program
6 · The paper itself

Abstract

Prostate cancer (PCa) is the most common malignancy in men and is the leading cause of cancer-related male mortality. A disulfide cyclic peptide ligand [CTVRTSADC]

Indexed as

Amino Acid SequenceAntineoplastic AgentsArea Under CurveCell DeathCell Line, TumorCell SurvivalDisulfidesDoxorubicinFibronectinsFluorescent DyesHumansHydrogen-Ion ConcentrationLigandsMalePeptidesProstatic NeoplasmsAntineoplastic AgentsDisulfidesDoxorubicinFibronectinsFluorescent DyesLigandsPeptidesantiproliferative assayconjugationdocetaxeldoxorubicinextra domain BfibronectinFmoc/tBupeptide–drug conjugateprostate cancersolid-phase synthesistargeting

Identifiers

PMID31277465
PMCPMC6651341
OpenAlexW2954414472

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.