Evidence map›Paper›PMID 31277423›Full record

ReviewMolecules (Basel, Switzerland)2019

Application of Porphyrins in Antibacterial Photodynamic Therapy.

Bamidele M Amos-Tautua, Sandile P Songca, Oluwatobi S Oluwafemi

Open access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 87 papers.

0numbers the graph read from it
0cells of the map it votes in
87citing papers in PubMed
23.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

87 citing papers in PubMed, 264 citations in OpenAlex.

  1. Trial
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  8. Antimicrobial photodynamic therapy using tetra-cationic porphyrins with peripheral platinum(II) and palladium(II) complexes against multidrug-resistant bacteria isolated from canine otitis.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2026
    Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Review
  15. First evidence of photoinactivation of rapidly growing mycobacteria by tetra-cationic porphyrins with peripheral cisplatin.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2025
    Article
  16. Review
  17. Cationic Bacteriochlorin in the photodynamic inactivation of microorganisms.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2025
    Article
  18. Review
  19. Article
  20. Article

27 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Bamidele M Amos-TautuaDepartment of Chemical Sciences, University of Johannesburg, Doornfontein Campus, P.O. Box 17011, Doornfontein 2028, South Africa.
Sandile P SongcaDepartment of Chemistry, University of KwaZulu-Natal, Private Bag X 54001, Durban 4000, South Africa.ORCID 0000-0003-2522-5567
Oluwatobi S OluwafemiDepartment of Chemical Sciences, University of Johannesburg, Doornfontein Campus, P.O. Box 17011, Doornfontein 2028, South Africa. oluwafemi.oluwatobi@gmail.com.ORCID 0000-0001-8964-5646
University of Johannesburg · ZAUniversity of KwaZulu-Natal · ZA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antibiotics are commonly used to control, treat, or prevent bacterial infections, however bacterial resistance to all known classes of traditional antibiotics has greatly increased in the past years especially in hospitals rendering certain therapies ineffective. To limit this emerging public health problem, there is a need to develop non-incursive, non-toxic, and new antimicrobial techniques that act more effectively and quicker than the current antibiotics. One of these effective techniques is antibacterial photodynamic therapy (aPDT). This review focuses on the application of porphyrins in the photo-inactivation of bacteria. Mechanisms of bacterial resistance and some of the current 'greener' methods of synthesis of meso-phenyl porphyrins are discussed. In addition, significance and limitations of aPDT are also discussed. Furthermore, we also elaborate on the current clinical applications and the future perspectives and directions of this non-antibiotic therapeutic strategy in combating infectious diseases.

Indexed as

PhotochemotherapyAnimalsAnti-Bacterial AgentsBacteriaHumansLightPorphyrinsAnti-Bacterial AgentsPorphyrinsantibacterial photodynamic therapybacterialightnanoparticlesporphyrins

Identifiers

PMID31277423
PMCPMC6650910
OpenAlexW2954110626

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.