ArticleBiosensors2019
Cyclic Olefin Copolymer Microfluidic Devices for Forensic Applications.
Article in Biosensors, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed.
- Enhancing Biocompatibility: 3D-Printed Cyclic Olefin Copolymer Structures for Advanced Laboratory Applications.3D printing and additive manufacturing · 2025Article
- Microfluidic Sensors Integrated with Smartphones for Applications in Forensics, Agriculture, and Environmental Monitoring.Micromachines · 2025Review
- The Evolution of Illicit-Drug Detection: From Conventional Approaches to Cutting-Edge Immunosensors-A Comprehensive Review.Biosensors · 2024Review
- High-Scale 3D-Bioprinting Platform for the Automated Production of Vascularized Organs-on-a-Chip.Advanced healthcare materials · 2024Article
- Rapid prototyping of PMMA-based microfluidic spheroid-on-a-chip models using micromilling and vapour-assisted thermal bonding.Scientific reports · 2024Article
- Scalable Processing of Cyclic Olefin Copolymer (COC) Microfluidic Biochips.Micromachines · 2023Article
- Synthesis and Characterization of Carbon Microbeads.ACS omega · 2023Article
- On the Application of Microfluidic-Based Technologies in Forensics: A Review.Sensors (Basel, Switzerland) · 2023Review
- Breaking the clean room barrier: exploring low-cost alternatives for microfluidic devices.Frontiers in bioengineering and biotechnology · 2023Review
- Polymeric Microfluidic Devices Fabricated Using Epoxy Resin for Chemically Demanding and Day-Long Experiments.Biosensors · 2022Article
- The Fabrication and Bonding of Thermoplastic Microfluidics: A Review.Materials (Basel, Switzerland) · 2022Review
- Bonding Strategies for Thermoplastics Applicable for Bioanalysis and Diagnostics.Micromachines · 2022Review
- Rapid, inexpensive fabrication of electrophoretic microdevices for fluorescence detection.Electrophoresis · 2022Article
- Rolling Circle Amplification-based Copper Nanoparticle Synthesis on Cyclic Olefin Copolymer Substrate and Its Application in Aptasensor.Biotechnology and bioprocess engineering : BBE · 2022Article
- Engineering 3D Printed Microfluidic Chips for the Fabrication of Nanomedicines.Pharmaceutics · 2021Article
- PCR-assisted impedimetric biosensor for colibactin-encoding pks genomic island detection in E. coli samples.Analytical and bioanalytical chemistry · 2021Article
- Fabrication and Applications of Microfluidic Devices: A Review.International journal of molecular sciences · 2021Review
- Rapid Manufacturing of Multilayered Microfluidic Devices for Organ on a Chip Applications.Sensors (Basel, Switzerland) · 2021Review
- Disposable DNA Amplification Chips with Integrated Low-Cost Heaters.Micromachines · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Microfluidic devices offer important benefits for forensic applications, in particular for fast tests at a crime scene. A large portion of forensic applications require microfluidic chip material to show compatibility with biochemical reactions (such as amplification reactions), and to have high transparency in the visible region and high chemical resistance. Also, preferably, manufacturing should be simple. The characteristic properties of cyclic olefin copolymer (COC) fulfills these requirements and offers new opportunities for the development of new forensic tests. In this work, the versatility of COC as material for lab-on-a-chip (LOC) systems in forensic applications has been explored by realizing two proof-of-principle devices. Chemical resistance and optical transparency were investigated for the development of an on-chip presumptive color test to indicate the presence of an illicit substance through applying absorption spectroscopy. Furthermore, the compatibility of COC with a DNA amplification reaction was verified by performing an on-chip multiple displacement amplification (MDA) reaction.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.