Evidence map›Paper›PMID 31277343›Full record

ReviewInternational journal of molecular sciences2019

Isoforms of Base Excision Repair Enzymes Produced by Alternative Splicing.

Elizaveta O Boldinova, Rafil F Khairullin, Alena V Makarova, Dmitry O Zharkov

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. 8-Oxoguanine: A Lesion, an Epigenetic Mark, or a Molecular Signal?International journal of molecular sciences · 2025
    Review
  3. Base Excision DNA Repair in Plants:International journal of molecular sciences · 2023
    Review
  4. Article
  5. Review
  6. Noncatalytic Domains in DNA Glycosylases.International journal of molecular sciences · 2022
    Review
  7. Article
  8. Review
  9. Review
  10. Review
  11. Review
  12. MUTYH: Not just polyposis.World journal of clinical oncology · 2020
    Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Elizaveta O BoldinovaRAS Institute of Molecular Genetics, 2 Kurchatova Sq., 123182 Moscow, Russia.
Rafil F KhairullinInstitute of Fundamental Medicine and Biology, Kazan (Volga Region) Federal University, 9 Parizhskoy Kommuny Str., 420012 Kazan, Russia.
Alena V MakarovaRAS Institute of Molecular Genetics, 2 Kurchatova Sq., 123182 Moscow, Russia. amakarova-img@yandex.ru.
Dmitry O ZharkovNovosibirsk State University, 1 Pirogova St., 630090 Novosibirsk, Russia. dzharkov@niboch.nsc.ru.
Institute of Molecular Genetics · RUKazan Federal University · RUNovosibirsk State University · RU

Funding

Russian Foundation for Basic Research 17-00-00263Russian Foundation for Basic Research 17-00-00264Russian Science Foundation 17-14-01190
6 · The paper itself

Abstract

Transcripts of many enzymes involved in base excision repair (BER) undergo extensive alternative splicing, but functions of the corresponding alternative splice variants remain largely unexplored. In this review, we cover the studies describing the common alternatively spliced isoforms and disease-associated variants of DNA glycosylases, AP-endonuclease 1, and DNA polymerase beta. We also discuss the roles of alternative splicing in the regulation of their expression, catalytic activities, and intracellular transport.

Indexed as

Alternative SplicingDNA RepairProtein IsoformsAnimalsDNA-(Apurinic or Apyrimidinic Site) LyaseDNA GlycosylasesDNA Polymerase betaDNA Repair EnzymesHumansMiceRatsRNA, MessengerDNA-(Apurinic or Apyrimidinic Site) LyaseDNA GlycosylasesDNA Polymerase betaDNA Repair EnzymesPOLB protein, humanProtein IsoformsRNA, Messengeralternative splicingapurinic/apyrimidinic endonucleaseDNA glycosylasesDNA polymerase beta

Identifiers

PMID31277343
PMCPMC6651865
OpenAlexW2953882262

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.