Evidence map›Paper›PMID 31277307›Full record

ArticleNanomaterials (Basel, Switzerland)2019

The Impact of Surface Functionalization on the Biophysical Properties of Silver Nanoparticles.

Agnieszka Borowik, Kamila Butowska, Kinga Konkel, Rafał Banasiuk, Natalia Derewonko, Dariusz Wyrzykowski, Mykola Davydenko, Vsevolod Cherepanov, Viktor Styopkin, Yuriy Prylutskyy and 3 more

Open access · goldAbstract read
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 53 citations in OpenAlex.

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  8. Exploring the Bioactive Potentials of CInternational journal of molecular sciences · 2022
    Article
  9. Review
  10. Nano Silver-Induced Toxicity and Associated Mechanisms.International journal of nanomedicine · 2022
    Review
  11. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 2 countries.

Agnieszka BorowikLaboratory of Biophysics, Intercollegiate Faculty of Biotechnology UG-MUG, University of Gdansk, 80-307 Gdansk, Poland.
Kamila ButowskaLaboratory of Biophysics, Intercollegiate Faculty of Biotechnology UG-MUG, University of Gdansk, 80-307 Gdansk, Poland.
Kinga KonkelLaboratory of Biophysics, Intercollegiate Faculty of Biotechnology UG-MUG, University of Gdansk, 80-307 Gdansk, Poland.
Rafał BanasiukLaboratory of Biologically Active Compounds, IFB UG-MUG, University of Gdansk, 80-307 Gdansk, Poland.
Natalia DerewonkoLaboratory of Virus Molecular Biology, IFB UG-MUG, University of Gdansk, 80-307 Gdansk, Poland.
Dariusz WyrzykowskiFaculty of Chemistry, University of Gdansk, 80-308 Gdansk, Poland.
Mykola DavydenkoDepartment of Biophysics and Medical Informatics, Taras Shevchenko National University of Kyiv, 01601 Kyiv, Ukraine.
Vsevolod CherepanovInstitute of Physics of NAS of Ukraine, 03028 Kyiv, Ukraine.ORCID 0000-0003-4649-1936
Viktor StyopkinInstitute of Physics of NAS of Ukraine, 03028 Kyiv, Ukraine.
Yuriy PrylutskyyDepartment of Biophysics and Medical Informatics, Taras Shevchenko National University of Kyiv, 01601 Kyiv, Ukraine.
Paweł PohlFaculty of Chemistry, Division of Analytic Chemistry and Chemical Metallurgy, Wroclaw University of Technology, 50-373 Wroclaw, Poland.ORCID 0000-0003-1844-7188
Aleksandra KrolickaLaboratory of Biologically Active Compounds, IFB UG-MUG, University of Gdansk, 80-307 Gdansk, Poland. aleksandra.krolicka@biotech.ug.edu.pl.ORCID 0000-0001-5231-283X
Jacek PiosikLaboratory of Biophysics, Intercollegiate Faculty of Biotechnology UG-MUG, University of Gdansk, 80-307 Gdansk, Poland. jacek.piosik@biotech.ug.edu.pl.ORCID 0000-0002-5671-1915
University of Gdańsk · PLInstitute of Physics · UATaras Shevchenko National University of Kyiv · UAWrocław University of Science and Technology · PL

Funding

University of Gdansk 538-M045-B025-18
6 · The paper itself

Abstract

Among metal-based nanoparticles, silver nanoparticles (AgNPs) are particularly appealing because of their stability, functionality, and documented antimicrobial properties. AgNPs also offer the possibility of different surface modifications. In this work, we functionalized AgNPs with thiobarbituric acid or 11-mercaptoundecanoic acid residues to improve the nanoparticles' biological activities. Subsequently, we assessed the physicochemical properties of newly synthesized AgNPs using a wide range of biophysical methodologies, including UV/vis and fluorescence spectroscopy, atomic force and scanning electron microscopy, and dynamic light scattering and isothermal titration calorimetry. Next, we examined the effect of nanoparticles functionalization on AgNPs mutagenicity and toxicity. Our study revealed that AgNPs' surface modification affects nanoparticles aggregation, and also impacts nanoparticles' interaction with model acridine mutagen ICR-191. AgNPs coated with MUA showed the most interesting interactions with tested ICR-191, slightly modulating its toxicity properties by decreasing the viability in treated cells.

Indexed as

Ames testmutagenicitysilver nanoparticlessurface functionalizationsynthesistoxicity

Identifiers

PMID31277307
PMCPMC6669631
OpenAlexW2954853625

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.