Evidence map›Paper›PMID 31277241›Full record

ArticleBioengineering (Basel, Switzerland)2019

Biomechanical Restoration Potential of Pentagalloyl Glucose after Arterial Extracellular Matrix Degeneration.

Sourav S Patnaik, Senol Piskin, Narasimha Rao Pillalamarri, Gabriela Romero, G Patricia Escobar, Eugene Sprague, Ender A Finol

Open access · goldAbstract read
In one paragraph

Article in Bioengineering (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Experimental mechanics · 2021
    Article
  9. Introduction to the Special Issue onBioengineering (Basel, Switzerland) · 2020
    Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Sourav S PatnaikDepartment of Mechanical Engineering, The University of Texas at San Antonio, One UTSA Circle, San Antonio, TX 78249, USA.
Senol PiskinDepartment of Mechanical Engineering, The University of Texas at San Antonio, One UTSA Circle, San Antonio, TX 78249, USA.ORCID 0000-0002-8799-9472
Narasimha Rao PillalamarriDepartment of Mechanical Engineering, The University of Texas at San Antonio, One UTSA Circle, San Antonio, TX 78249, USA.
Gabriela RomeroChemical Engineering Program, Department of Biomedical Engineering, The University of Texas at San Antonio, San Antonio, TX 78249, USA.
G Patricia EscobarDepartment of Medicine, University of Texas Health San Antonio, San Antonio, TX 78229, USA.
Eugene SpragueDepartment of Medicine, University of Texas Health San Antonio, San Antonio, TX 78229, USA.
Ender A FinolDepartment of Mechanical Engineering, The University of Texas at San Antonio, One UTSA Circle, San Antonio, TX 78249, USA. ender.finol@utsa.edu.ORCID 0000-0002-0811-9482
The University of Texas at San Antonio · USThe University of Texas Health Science Center at San Antonio · USKoç University · TR

Funding

American Heart Association 16CSA28480006National Institutes of Health R01HL121293
6 · The paper itself

Abstract

The objective of this study was to quantify pentagalloyl glucose (PGG) mediated biomechanical restoration of degenerated extracellular matrix (ECM). Planar biaxial tensile testing was performed for native (N), enzyme-treated (collagenase and elastase) (E), and PGG (P) treated porcine abdominal aorta specimens (n = 6 per group). An Ogden material model was fitted to the stress-strain data and finite element computational analyses of simulated native aorta and aneurysmal abdominal aorta were performed. The maximum tensile stress of the N group was higher than that in both E and P groups for both circumferential (43.78 ± 14.18 kPa vs. 10.03 ± 2.68 kPa vs. 13.85 ± 3.02 kPa;

Indexed as

aneurysmaortabiomechanicsenzymepentagalloyl glucose

Identifiers

PMID31277241
PMCPMC6783915
OpenAlexW2956069648

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.