Evidence map›Paper›PMID 31277238›Full record

ArticleBiomolecules2019

Betulinic Acid Suppresses Ovarian Cancer Cell Proliferation through Induction of Apoptosis.

Dahae Lee, Seoung Rak Lee, Ki Sung Kang, Yuri Ko, Changhyun Pang, Noriko Yamabe, Ki Hyun Kim

Open access · goldAbstract read
In one paragraph

Article in Biomolecules, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 55 citations in OpenAlex.

  1. Betulinic acid isolated fromHistology and histopathology · 2026
    Article
  2. Review
  3. Article
  4. Review
  5. Review
  6. Review
  7. Article
  8. Betulinic acid and obesity-related disorders.Frontiers in pharmacology · 2025
    Review
  9. Article
  10. Review
  11. Article
  12. Review
  13. Review
  14. Review
  15. Review
  16. Review
  17. Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Dahae LeeSchool of Pharmacy, Sungkyunkwan University, Suwon 16419, Korea.
Seoung Rak LeeSchool of Pharmacy, Sungkyunkwan University, Suwon 16419, Korea.
Ki Sung KangCollege of Korean Medicine, Gachon University, Seongnam 13120, Korea.
Yuri KoDepartment of Obstetrics and Gynecology, University of Ulsan, Asan Medical Center, Seoul 05505, Korea.
Changhyun PangSchool of Chemical Engineering, Sungkyunkwan University, Suwon 16419, Korea.
Noriko YamabeCollege of Korean Medicine, Gachon University, Seongnam 13120, Korea. norikoy@gachon.ac.kr.
Ki Hyun KimSchool of Pharmacy, Sungkyunkwan University, Suwon 16419, Korea. khkim83@skku.edu.ORCID 0000-0002-5285-9138
Sungkyunkwan University · KRGachon University · KRAsan Medical Center · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ovarian cancer is one of the leading causes of cancer deaths worldwide in women, and the most malignant cancer among the different gynecological cancers. In this study, we explored potentially anticancer compounds from

Indexed as

Antineoplastic Agents, PhytogenicApoptosisBetulinic AcidCell ProliferationCell SurvivalCornaceaeDose-Response Relationship, DrugDrug Screening Assays, AntitumorFemaleHumansMolecular ConformationPentacyclic TriterpenesPlant BarkPlant ExtractsPlant StemsStructure-Activity RelationshipAntineoplastic Agents, PhytogenicBetulinic AcidPentacyclic TriterpenesPlant ExtractsTriterpenesapoptosisbetulinic acidCornus walterimitochondria-dependent pathwaymitochondria-independent pathwayovarian cancer

Identifiers

PMID31277238
PMCPMC6681197
OpenAlexW2955698429

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.