Observational studyMedicine2019
Predicting factors of lateral neck lymph node metastases in patients with papillary thyroid microcarcinoma.
Observational study in Medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 26 citations in OpenAlex.
- Which is preferred for initial treatment of papillary thyroid cancer, total thyroidectomy or lobotomy?Cancer medicine · 2021Trial
- Article
- Pretreatment level of circulating tumor cells is associated with lymph node metastasis in papillary thyroid carcinoma patients with ≤ 55 years old.World journal of surgical oncology · 2025Article
- Risk factors for lateral cervical lymph node metastasis in papillary thyroid carcinoma and to develop and validate a nomogram model.Frontiers in endocrinology · 2025Article
- Risk factors and distribution pattern of lateral lymph node recurrence after central neck dissection for cN1a papillary thyroid carcinoma.BMC surgery · 2024Article
- Prospective application of a prediction model for lateral lymph node metastasis in papillary thyroid cancer patients with central lymph node metastasis.Frontiers in endocrinology · 2023Article
- Lateral Involvement in Different Sized Papillary Thyroid Carcinomas Patients with Central Lymph Node Metastasis: A Multi-Center Analysis.Journal of clinical medicine · 2022Article
- Machine learning-based dynamic prediction of lateral lymph node metastasis in patients with papillary thyroid cancer.Frontiers in endocrinology · 2022Article
- Pathology confirmation of the efficacy and safety of microwave ablation in papillary thyroid carcinoma.Frontiers in endocrinology · 2022Article
- Total thyroidectomy is superior for initial treatment of thyroid cancer.Asia-Pacific journal of clinical oncology · 2021Article
- Predicting factors of central lymph node metastasis and BRAFWorld journal of surgical oncology · 2021Article
- Features of Lymph Node Metastasis and Structural Recurrence in Papillary Thyroid Carcinoma Located in the Upper Portion of the Thyroid: A Retrospective Cohort Study.Frontiers in endocrinology · 2021Article
- Article
- The effectiveness of prophylactic ipsilateral central neck dissection in selected patients who underwent total thyroidectomy for clinically node-negative unilateral papillary thyroid carcinoma.Yeungnam University journal of medicine · 2020Article
- Predictive factors for central lymph node metastases in papillary thyroid microcarcinoma.World journal of clinical cases · 2020Review
- Management of Lateral Multiple-Level Metastasis in N1b Papillary Thyroid Microcarcinoma.Frontiers in oncology · 2020Article
- With High-Risk Factors, Total Thyroidectomy is Preferred for Thyroid Cancer.Cancer management and research · 2020Article
- Clinicopathological Findings Associated With Cervical Lymph Node Metastasis in Papillary Thyroid Microcarcinoma: A Retrospective Study in China.Cancer control : journal of the Moffitt Cancer CenterArticle
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The incidence of papillary thyroid microcarcinoma (PTMC) has increased dramatically in recent years. Compared with central lymph node metastases, lateral neck lymph node (LNLN) metastases in patients with PTMC were less studied. The aim of the present study is to analyze the predicting factors associated with LNLN metastases in patients with PTMC.A total of 3514 patients underwent thyroid surgery at our hospital from January 2017 to December 2017, and 936 patients with PTMC were selected and assessed retrospectively. They were further divided into 2 groups based on whether LNLN metastases existed or not. The relationship between LNLN metastases and clinicopathologic features of PTMC was analyzed.LNLN metastases were confirmed in 126 patients. Univariate and multivariate analyses found 5 independent factors associated with LNLN metastases. They were tumor size (≥0.7 cm) [odds ratio (OR) = 1.960, 95% confidence interval (95% CI) 1.227-3.131; P = .005], multifocality (OR = 2.254, 95% CI 1.398-3.634; P = .001), tumor location (upper portion) (OR = 6.312, 95% CI 3.853-10.340; P < .001), thyroid cancer family history (OR = 7.727, 95% CI 2.227-26.818; P = .001), and central lymph node metastases (OR = 11.810, 95% CI 6.547-21.302; P < .001).The findings of our study indicated that LNLN metastases were not rare in patients with PTMC, and tumor size (≥0.7 cm), multifocality, tumor location (upper portion), thyroid cancer family history, and central lymph node metastases were independent factors for LNLN metastases. In order to perform individualized management, LNLN should be meticulously evaluated when these features are detected.
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