Trial reportJournal of cardiac failure2019
Pediatric Heart Transplantation: Transitioning to Adult Care (TRANSIT): Feasibility of a Pilot Randomized Controlled Trial.
Trial report in Journal of cardiac failure, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 29 citations in OpenAlex.
- Patient navigator programmes for children and adolescents with chronic diseases.The Cochrane database of systematic reviews · 2024Pooled it
- Efficacy of Adherence-Enhancing Interventions for Immunosuppressive Therapy in Solid Organ Transplant Recipients: A Systematic Review and Meta-Analysis Based on Randomized Controlled Trials.Frontiers in pharmacology · 2020Pooled it
- Clinical outcomes of pediatric heart transplantation: A 25-year follow-up experience in a Japanese institute.JTCVS open · 2026Article
- Transition from pediatric to adult care in thoracic transplantation-Challenges and opportunities.JHLT open · 2025Article
- Article
- Palliative care for the cardiothoracic transplant recipient.JHLT open · 2025Article
- Into Adulthood: Assessing Parental Perceptions and Concerns for Pediatric Heart Transplant Recipients Around the Transition Into Adult Care.Pediatric transplantation · 2025Article
- Modification and scoring of a transition tool to understand transition readiness among pediatric kidney transplant recipients.Pediatric nephrology (Berlin, Germany) · 2025Observational
- Immunosuppressant adherence after heart transplantation: a review on detection, prevention, and intervention strategies in a multidisciplinary.Frontiers in cardiovascular medicine · 2025Review
- Health care transition planning and outcomes: What's next?Health care transitions · 2024Article
- The improving Medication Adherence in Adolescents and young adults following Liver Transplantation (iMALT) multisite trial: Design and trial implementation considerations.Clinical trials (London, England) · 2023Article
- A Systematic Review of Adherence to Immunosuppression among Pediatric Heart Transplant Patients.Journal of cardiovascular development and disease · 2022Review
- Are we ready for building transition programs for heart transplant recipients in Japan? - Knowing the unique background is the first step for discussion.Frontiers in pediatrics · 2022Article
- Adherence to Medication During Transition to Adult Services.Paediatric drugs · 2020Review
Corrections and comments
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Authors and funding
19 authors at 10 institutions in 1 country.
Funding
Abstract
backgroundYoung-adult heart transplant recipients transferring to adult care are at risk for poor health outcomes. We conducted a pilot randomized controlled trial to determine the feasibility of and to test a transition intervention for young adults who underwent heart transplantation as children and then transferred to adult care.
methodsParticipants were randomized to the transition intervention (4 months long, focused on heart-transplant knowledge, self-care, self-advocacy, and social support) or usual care. Self-report questionnaires and medical records data were collected at baseline and 3 and 6 months after the initial adult clinic visit. Longitudinal analyses comparing outcomes over time were performed using generalized estimating equations and linear mixed models.
resultsTransfer to adult care was successful and feasible (ie, excellent participation rates). The average patient standard deviation of mean tacrolimus levels was similar over time in both study arms and < 2.5, indicating adequate adherence. There were no between-group or within-group differences in percentage of tacrolimus bioassays within target range (> 50%). Average overall adherence to treatment was similarly good in both groups. Rates of appointment keeping through 6 months after transfer declined over time in both groups.
conclusionsThe feasibility of the study was demonstrated. Our transition intervention did not improve outcomes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.